Pub. Date : 1976 Nov
PMID : 10077
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It is suggested that under the conditions used here the following different processes may have contributed to the total incorporation of BP products into nuclear DNA: (a) formation of DNA-binding products derived from BP by nuclear aryl hydrocarbon hydroxylase; (b) formation of DNA-binding products from microsomal BP metabolites by nuclear aryl hydrocarbon hydroxylase; and (c) direct transfer of reactive microsomal metabolites to nuclear DNA. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 1 | Rattus norvegicus |
| 2 | It is suggested that under the conditions used here the following different processes may have contributed to the total incorporation of BP products into nuclear DNA: (a) formation of DNA-binding products derived from BP by nuclear aryl hydrocarbon hydroxylase; (b) formation of DNA-binding products from microsomal BP metabolites by nuclear aryl hydrocarbon hydroxylase; and (c) direct transfer of reactive microsomal metabolites to nuclear DNA. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 1 | Rattus norvegicus |
| 3 | It is suggested that under the conditions used here the following different processes may have contributed to the total incorporation of BP products into nuclear DNA: (a) formation of DNA-binding products derived from BP by nuclear aryl hydrocarbon hydroxylase; (b) formation of DNA-binding products from microsomal BP metabolites by nuclear aryl hydrocarbon hydroxylase; and (c) direct transfer of reactive microsomal metabolites to nuclear DNA. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 1 | Rattus norvegicus |
| 4 | It is suggested that under the conditions used here the following different processes may have contributed to the total incorporation of BP products into nuclear DNA: (a) formation of DNA-binding products derived from BP by nuclear aryl hydrocarbon hydroxylase; (b) formation of DNA-binding products from microsomal BP metabolites by nuclear aryl hydrocarbon hydroxylase; and (c) direct transfer of reactive microsomal metabolites to nuclear DNA. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 1 | Rattus norvegicus |