Pub. Date : 1999 Mar
PMID : 10076178
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study examined whether type 1 angiotensin II receptor (AT1) and angiotensin-converting enzyme (ACE) mRNAs are regulated during dietary salt loading in angiotensinogen gene-knockout (Atg-/-) mice which are genetically deficient in endogenous production of angiotensin II. | Salts | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | Mus musculus |
| 2 | Salt loading also enhanced renal cortex ACE mRNA levels in Atg+/+ mice. | Salts | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | Mus musculus |
| 3 | Thus, expression of AT1 and ACE is regulated by salt loading in a tissue-specific manner that appears to be mediated, at least partly, by a mechanism other than changes in the circulating or tissue levels of angiotensin peptides. | Salts | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | Mus musculus |