Title : Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines.

Pub. Date : 1999 Mar 3

PMID : 10070941






1 Functional Relationships(s)
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1 BACKGROUND: Human cancer cell lines grown in the presence of the cytotoxic agent mitoxantrone frequently develop resistance associated with a reduction in intracellular drug accumulation without increased expression of the known drug resistance transporters P-glycoprotein and multidrug resistance protein (also known as multidrug resistance-associated protein). Mitoxantrone ATP binding cassette subfamily B member 1 Homo sapiens