Title : Tumor necrosis factor-alpha and ceramide induce cell death through different mechanisms in rat mesangial cells.

Pub. Date : 1999 Mar

PMID : 10070162






2 Functional Relationships(s)
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1 Our results indicate that although C2 ceramide was toxic to mesangial cells, the cell death it induced differed both morphologically and biochemically from that induced by TNF-alpha in the presence of cycloheximide (CHX). Cycloheximide tumor necrosis factor Rattus norvegicus
2 Furthermore, the cleavage of cytosolic phospholipase A2 during cell death induced by C2 ceramide and by TNF-alpha in the presence of CHX showed distinctive patterns. Cycloheximide tumor necrosis factor Rattus norvegicus