Title : TNF-alpha upregulates Gialpha and Gqalpha protein expression and function in human airway smooth muscle cells.

Pub. Date : 1999 Mar

PMID : 10070103






1 Functional Relationships(s)
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1 TNF-alpha treatment for 72 h significantly increased the expression of Galphai-2 and Gqalpha proteins and enhanced carbachol (10(-7) M)-mediated inhibition of adenylyl cyclase activity and inositol phosphate synthesis. Inositol Phosphates tumor necrosis factor Homo sapiens