Pub. Date : 1999 Feb
PMID : 10064335
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of AP-1 by the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) is essential to tumor promotion. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 2 | Induction of AP-1 by the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) is essential to tumor promotion. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 3 | We propose that this results in attenuation in the induction of the AP-1 transcription factor by TPA. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |
| 4 | Because AP-1 induction by TPA is obligatory for mouse skin promotion, we propose this as an essential component of the mechanism of DER prevention of mouse skin carcinogenesis. | Tetradecanoylphorbol Acetate | jun proto-oncogene | Mus musculus |