Pub. Date : 1999 Mar 2
PMID : 10051602
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | FKBP52 (FKBP59, FKBP4) is a "macro" immunophilin that, although sharing high structural and functional homologies in its amino-terminal domain with FKBP12 (FKBP1), does not have immunosuppressant activity when complexed with FK506, unlike FKBP12. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |
| 2 | FKBP52 (FKBP59, FKBP4) is a "macro" immunophilin that, although sharing high structural and functional homologies in its amino-terminal domain with FKBP12 (FKBP1), does not have immunosuppressant activity when complexed with FK506, unlike FKBP12. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |
| 3 | FKBP52 (FKBP59, FKBP4) is a "macro" immunophilin that, although sharing high structural and functional homologies in its amino-terminal domain with FKBP12 (FKBP1), does not have immunosuppressant activity when complexed with FK506, unlike FKBP12. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |
| 4 | Whereas the binding of calcineurin to FKBP12 is potentiated by FK506, the specific association of PAHX and FKBP52 is maintained in the presence of FK506. | Tacrolimus | FKBP prolyl isomerase 4 | Homo sapiens |