Title : Unexpected crucial role of residue 225 in serine proteases.

Pub. Date : 1999 Mar 2

PMID : 10051558






1 Functional Relationships(s)
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1 The activity profiles obtained for thrombin also suggest that the conversion of Pro to Tyr or Phe documented in the vertebrates occurred through Ser and was driven by a significant gain (up to 50-fold) in catalytic activity. Proline coagulation factor II, thrombin Homo sapiens