Title : A single hydrophobic residue confers barbiturate sensitivity to gamma-aminobutyric acid type C receptor.

Pub. Date : 1999 Mar

PMID : 10051524






1 Functional Relationships(s)
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1 Barbiturate sensitivity was imparted to the human rho1 homooligomeric gamma-aminobutyric acid (GABA) receptor channel by mutation of a tryptophan residue at position 328 (Trp328), which is located within the third transmembrane domain. barbituric acid GABA type A receptor-associated protein Homo sapiens