Title : Direct interaction between a quinoline derivative, MS-209, and multidrug resistance protein (MRP) in human gastric cancer cells.

Pub. Date : 1999 Feb 24

PMID : 10049760






1 Functional Relationships(s)
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1 In both resistant and unselected cell lines expressing the MRP gene, MS-209 increased [3H]vincristine accumulation in proportion with the level of MRP mRNA expression and enhanced the cytotoxicity of etoposide, doxorubicin, and vincristine. Doxorubicin ATP binding cassette subfamily C member 1 Homo sapiens