Title : Formation of phosphatidic acid and subclasses of phosphatidylethanol in human neutrophils upon interleukin-8 stimulation.

Pub. Date : 1999 Feb

PMID : 10048791






4 Functional Relationships(s)
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1 Previous studies showed that interleukin-8 (IL-8) stimulates phospholipase D hydrolysis of phosphatidylcholine to generate phosphatidic acid in human neutrophils. Phosphatidylcholines C-X-C motif chemokine ligand 8 Homo sapiens
2 Previous studies showed that interleukin-8 (IL-8) stimulates phospholipase D hydrolysis of phosphatidylcholine to generate phosphatidic acid in human neutrophils. Phosphatidylcholines C-X-C motif chemokine ligand 8 Homo sapiens
3 No studies have examined phospholipase D hydrolysis of the three subclasses of phosphatidylcholine in interleukin-8-stimulated neutrophils. Phosphatidylcholines C-X-C motif chemokine ligand 8 Homo sapiens
4 Our findings suggest that phospholipase D catalyses the hydrolysis of diacyl, alkylacyl and alkenylacyl subclasses of phosphatidylcholine in neutrophils upon IL-8 stimulation. Phosphatidylcholines C-X-C motif chemokine ligand 8 Homo sapiens