Title : Phenobarbital induction of CYP2B1/2 in primary hepatocytes: endocrine regulation and evidence for a single pathway for multiple inducers.

Pub. Date : 1999 Feb 15

PMID : 10036216






2 Functional Relationships(s)
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Protein Name
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1 Phenobarbital (PB) and many structurally unrelated chemicals induce the protein and mRNA of P450 cytochromes CYP2B1, CYP2B2, CYP3A1, and specific phase II enzymes to a greater extent in Fischer 344 (F344) than in Wistar Furth (WF) female rats. Phenobarbital cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 Rattus norvegicus
2 Phenobarbital (PB) and many structurally unrelated chemicals induce the protein and mRNA of P450 cytochromes CYP2B1, CYP2B2, CYP3A1, and specific phase II enzymes to a greater extent in Fischer 344 (F344) than in Wistar Furth (WF) female rats. Phenobarbital cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 Rattus norvegicus