Title : Negative regulation of MDR1 promoter activity in MCF-7, but not in multidrug resistant MCF-7/Adr, cells by cross-coupled NF-kappa B/p65 and c-Fos transcription factors and their interaction with the CAAT region.

Pub. Date : 1999 Feb 16

PMID : 10026303






4 Functional Relationships(s)
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Protein Name
Organism
1 After treatment of MCF-7 cells with cycloheximide (CHX), MDR1 mRNA reached detectable levels, suggesting that MDR1 mRNA expression might be controlled by a labile negative regulatory protein(s) in MCF-7 cells. Cycloheximide ATP binding cassette subfamily B member 1 Homo sapiens
2 After treatment of MCF-7 cells with cycloheximide (CHX), MDR1 mRNA reached detectable levels, suggesting that MDR1 mRNA expression might be controlled by a labile negative regulatory protein(s) in MCF-7 cells. Cycloheximide ATP binding cassette subfamily B member 1 Homo sapiens
3 After treatment of MCF-7 cells with cycloheximide (CHX), MDR1 mRNA reached detectable levels, suggesting that MDR1 mRNA expression might be controlled by a labile negative regulatory protein(s) in MCF-7 cells. Cycloheximide ATP binding cassette subfamily B member 1 Homo sapiens
4 After treatment of MCF-7 cells with cycloheximide (CHX), MDR1 mRNA reached detectable levels, suggesting that MDR1 mRNA expression might be controlled by a labile negative regulatory protein(s) in MCF-7 cells. Cycloheximide ATP binding cassette subfamily B member 1 Homo sapiens