Title : Experimental and clinical toxicology of anticholinesterase agents.

Pub. Date : 1998 Dec 28

PMID : 10022304






1 Functional Relationships(s)
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1 Their acute toxic effect in the central and peripheral nervous system is due to inhibition of acetylcholinesterase (AChE) at nerve endings which causes accumulation of acetylcholine and consequently overstimulation of the nicotinic and muscarinic receptors. Acetylcholine acetylcholinesterase (Cartwright blood group) Homo sapiens