Decitabine

phosphatase and tensin homolog ; Homo sapiens







19 Article(s)
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1 35628480 Epigenetic Silencing of PTEN and Epi-Transcriptional Silencing of MDM2 Underlied Progression to Secondary Acute Myeloid Leukemia in Myelodysplastic Syndrome Treated with Hypomethylating Agents. 2022 May 18 1
2 33747197 Decitabine inhibits the proliferation of human T-cell acute lymphoblastic leukemia molt4 cells and promotes apoptosis partly by regulating the PI3K/AKT/mTOR pathway. 2021 May 3
3 33843428 SPAG6-silencing enhances decitabine-induced apoptosis and demethylation of PTEN in SKM-1 cells and in a xenograft mouse model. 2021 Sep 1
4 32546428 Loss of PTEN sensitizes head and neck squamous cell carcinoma to 5-AZA-2'-deoxycytidine. 2020 Aug 1
5 32572896 Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data. 2020 Jun 2
6 30912184 The effect of decitabine on the expression and methylation of the PPP1CA, BTG2, and PTEN in association with changes in miR-125b, miR-17, and miR-181b in NALM6 cell line. 2019 Aug 1
7 29499938 MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4BDCAF13 E3 Ligase in Osteosarcoma Cells. 2018 Mar 2 1
8 28152502 Methylation decreases the Bin1 tumor suppressor in ESCC and restoration by decitabine inhibits the epithelial mesenchymal transition. 2017 Mar 21 2
9 25638724 CpG hypermethylation contributes to decreased expression of PTEN during acquired resistance to gefitinib in human lung cancer cell lines. 2015 Mar 1
10 24604064 Aberrant CpG island methylation of PTEN is an early event in nasopharyngeal carcinoma and a potential diagnostic biomarker. 2014 May 3
11 25024751 Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples. 2014 2
12 22967388 [Effect of proliferation inhibition and PTEN gene expression induced by decitabine combined with daunorubicin on HL-60 cell line]. 2012 Jun 1
13 21170675 Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells. 2011 Nov 2
14 20089040 Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation. 2010 Feb 2
15 21472313 Methylation status of the PTEN gene in adenoid cystic carcinoma cells. 2010 Sep-Oct 1
16 17942153 Resistance to Imatinib Mesylate-induced apoptosis in acute lymphoblastic leukemia is associated with PTEN down-regulation due to promoter hypermethylation. 2008 May 1
17 16818626 Epigenetic silencing of the PTEN gene in melanoma. 2006 Jul 1 1
18 12006535 Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation. 2002 May 1
19 9560261 Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression. 1998 Apr 28 2