Glucose

glucagon ; Mus musculus







398 Article(s)
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1 34773257 A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome. 2022 Jun 1
2 34986353 Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion. 2022 Jan 4 1
3 35017714 E4orf1-induced reduction in endogenous insulin level is independent of pancreas endocrine function. 2022 May 1
4 35088915 A novel DPP-4 inhibitor Gramcyclin A attenuates cognitive deficits in APP/PS1/tau triple transgenic mice via enhancing brain GLP-1-dependent glucose uptake. 2022 Mar 2
5 35147704 The Essential Role of Pancreatic α-Cells in Maternal Metabolic Adaptation to Pregnancy. 2022 May 1 1
6 35202915 Small-molecule albumin ligand modification to enhance the anti-diabetic ability of GLP-1 derivatives. 2022 Apr 1
7 35399667 Dietary Medium-Chain Triglyceride Decanoate Affects Glucose Homeostasis Through GPR84-Mediated GLP-1 Secretion in Mice. 2022 1
8 35421610 Glucose inhibits glucagon secretion by decreasing [Ca2+]c and by reducing the efficacy of Ca2+ on exocytosis via somatostatin-dependent and independent mechanisms. 2022 Jul 4
9 35424534 Thiazolidinedione derivatives as novel GPR120 agonists for the treatment of type 2 diabetes. 2022 Feb 16 1
10 35439540 Metabolic effects of combined glucagon receptor antagonism and glucagon-like peptide-1 receptor agonism in high fat fed mice. 2022 Aug 1
11 35456981 Glucagon-like Peptide-1 Secretion Is Inhibited by Lysophosphatidic Acid. 2022 Apr 9 1
12 35484823 A GLP-1/glucagon (GCG)/CCK2 receptors tri-agonist provides new therapy for obesity and diabetes. 2022 Apr 28 2
13 35571083 Co-Crystal of Rosiglitazone With Berberine Ameliorates Hyperglycemia and Insulin Resistance Through the PI3K/AKT/TXNIP Pathway In Vivo and In Vitro. 2022 1
14 32473615 Display of quintuple glucagon-like peptide 1 (28-36) nonapeptide on Bacillus subtilis spore for oral administration in the treatment of type 2 diabetes. 2021 Feb 1
15 32790843 Glucagonotropic and Glucagonostatic Effects of KATP Channel Closure and Potassium Depolarization. 2021 Jan 1 3
16 33043402 Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets. 2021 Jan 2
17 33239450 Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia. 2021 Feb 1
18 33369112 Glucose-induced cAMP elevation in β-cells involves amplification of constitutive and glucagon-activated GLP-1 receptor signalling. 2021 Apr 1
19 33405187 A Rodent Model of Jejunal-Ileal Loop Bipartition (JILB): a Novel Malabsorptive Operation. 2021 Mar 1
20 33421947 A novel GLP-1 and FGF21 dual agonist has therapeutic potential for diabetes and non-alcoholic steatohepatitis. 2021 Jan 1
21 33434183 Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner. 2021 Feb 22 3
22 33434430 Structure-Activity Relationship and Biological Investigation of SR18292 (16), a Suppressor of Glucagon-Induced Glucose Production. 2021 Jan 28 2
23 33484949 Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice. 2021 Mar 1
24 33561965 High β-Glucan Barley Supplementation Improves Glucose Tolerance by Increasing GLP-1 Secretion in Diet-Induced Obesity Mice. 2021 Feb 6 1
25 33588950 Mesenchymal stem cells modified by FGF21 and GLP1 ameliorate lipid metabolism while reducing blood glucose in type 2 diabetic mice. 2021 Feb 15 2
26 33610858 Genetic activation of α-cell glucokinase in mice causes enhanced glucose-suppression of glucagon secretion during normal and diabetic states. 2021 Jul 2
27 33627316 Glucolipotoxicity and GLP-1 secretion. 2021 Feb 1
28 33636577 Matrine, as a CaSR agonist promotes intestinal GLP-1 secretion and improves insulin resistance in diabetes mellitus. 2021 Apr 1
29 33641163 The 14-3-3 protein YWHAB inhibits glucagon-induced hepatic gluconeogenesis through interacting with the glucagon receptor and FOXO1. 2021 May 1
30 33839150 Insulin receptor substrate 1, but not IRS2, plays a dominant role in regulating pancreatic alpha cell function in mice. 2021 Jan-Jun 1
31 33911126 Discovery, optimization, and evaluation of non-bile acid FXR/TGR5 dual agonists. 2021 Apr 28 1
32 33957303 Fasting Hormones Synergistically Induce Amino Acid Catabolism Genes to Promote Gluconeogenesis. 2021 1
33 34002801 Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver-α-cell axis. 2021 Jun 25 1
34 34054734 Benefits of Sustained Upregulated Unimolecular GLP-1 and CCK Receptor Signalling in Obesity-Diabetes. 2021 1
35 34095876 GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys. 2021 May 18 2
36 34118477 KATP channel blockers control glucagon secretion by distinct mechanisms: A direct stimulation of α-cells involving a [Ca2+]c rise and an indirect inhibition mediated by somatostatin. 2021 Nov 1
37 34122340 The Insulin Response to Oral Glucose in GIP and GLP-1 Receptor Knockout Mice: Review of the Literature and Stepwise Glucose Dose Response Studies in Female Mice. 2021 3
38 34168616 Gastrointestinal Distension by Pectin-Containing Carbonated Solution Suppresses Food Intake and Enhances Glucose Tolerance via GLP-1 Secretion and Vagal Afferent Activation. 2021 1
39 34168617 Impact of Incretin Hormone Receptors on Insulin-Independent Glucose Disposal in Model Experiments in Mice. 2021 3
40 34221868 Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide (GLP-1) secretion function of the mouse intestine. 2021 Jun 3
41 34246804 β-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs. 2021 Nov 1
42 34280305 Glucose-Fueled Peptide Assembly: Glucagon Delivery via Enzymatic Actuation. 2021 Aug 18 10
43 34284984 A method for constructing GLP-1 overexpression intestinal organoids. 2021 Jul 20 1
44 34356378 Purification, Physicochemical Properties, and Antioxidant Activities of Two Low-Molecular-Weight Polysaccharides from Ganoderma leucocontextum Fruiting Bodies. 2021 Jul 20 1
45 34444712 Storage and Utilization of Glycogen by Mouse Liver during Adaptation to Nutritional Changes Are GLP-1 and PASK Dependent. 2021 Jul 26 2
46 34520858 L-cell Arntl is required for rhythmic glucagon-like peptide-1 secretion and maintenance of intestinal homeostasis. 2021 Dec 1
47 34547355 Glucagon-like peptide-1 and beta cell glucose sensitivity - a glucose ramp study in mice. 2021 Dec 3
48 34572144 Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose. 2021 Sep 21 1
49 34639136 Lecithin Inclusion by α-Cyclodextrin Activates SREBP2 Signaling in the Gut and Ameliorates Postprandial Hyperglycemia. 2021 Oct 6 2
50 34647524 Hnf4g invalidation prevents diet-induced obesity via intestinal lipid malabsorption. 2021 Nov 24 2