| 1 |
33319444 | The effect of acute morphine on sleep in male patients suffering from sleep apnea: Is there a genetic effect? An RCT Study. | 2021 Aug |
1 |
| 2 |
33661919 | Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children. | 2021 Mar |
4 |
| 3 |
33847389 | Pharmacogenomics and Morphine. | 2021 Sep |
1 |
| 4 |
31738228 | A functional polymorphism in the ATP-Binding Cassette B1 transporter predicts pharmacologic response to combination of nortriptyline and morphine in neuropathic pain patients. | 2020 Mar |
2 |
| 5 |
30709768 | Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months. | 2019 Feb |
1 |
| 6 |
29870475 | Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report. | 2018 Jul |
1 |
| 7 |
30050319 | Super analgesia of intrathecal morphine may be related to ABCB1 (MDR1) gene polymorphism. | 2018 |
4 |
| 8 |
28474563 | Opioids and the Blood-Brain Barrier: A Dynamic Interaction with Consequences on Drug Disposition in Brain. | 2017 Nov 14 |
3 |
| 9 |
26751618 | Oral Morphine Pharmacokinetic in Obesity: The Role of P-Glycoprotein, MRP2, MRP3, UGT2B7, and CYP3A4 Jejunal Contents and Obesity-Associated Biomarkers. | 2016 Mar 7 |
1 |
| 10 |
27061230 | The ABCB1, rs9282564, AG and TT Genotypes and the COMT, rs4680, AA Genotype are Less Frequent in Deceased Patients with Opioid Addiction than in Living Patients with Opioid Addiction. | 2016 Oct |
3 |
| 11 |
27152241 | Morphine modulates doxorubicin uptake and improves efficacy of chemotherapy in an intracranial xenograft model of human glioblastoma. | 2016 |
4 |
| 12 |
25311385 | Opioid-induced respiratory depression: ABCB1 transporter pharmacogenetics. | 2015 Apr |
4 |
| 13 |
25809606 | Genotyping test with clinical factors: better management of acute postoperative pain? | 2015 Mar 19 |
3 |
| 14 |
25938863 | Identification of Possible Binding Sites for Morphine and Nicardipine on the Multidrug Transporter P-Glycoprotein Using Umbrella Sampling Techniques. | 2015 Jun 22 |
1 |
| 15 |
25948304 | [The blood-brain barrier transport mechanism controlling analgesic effects of opioid drugs in CNS]. | 2015 |
4 |
| 16 |
26086643 | The ontogeny of P-glycoprotein in the developing human blood-brain barrier: implication for opioid toxicity in neonates. | 2015 Oct |
3 |
| 17 |
26678969 | Clinical Implications of Opioid Pharmacogenomics in Patients With Cancer. | 2015 Oct |
1 |
| 18 |
24703092 | Influence of UGT2B7, OPRM1 and ABCB1 gene polymorphisms on postoperative morphine consumption. | 2014 Nov |
2 |
| 19 |
24747667 | Codeine-related deaths: The role of pharmacogenetics and drug interactions. | 2014 Jun |
1 |
| 20 |
24779372 | Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogenetics. | 2014 Apr 29 |
1 |
| 21 |
24882643 | [Effect of repeated oral treatment with etoposide on the expression of intestinal P-glycoprotein and oral morphine analgesia]. | 2014 |
1 |
| 22 |
25048710 | Involvement of moesin in the development of morphine analgesic tolerance through P-glycoprotein at the blood-brain barrier. | 2014 |
4 |
| 23 |
25155932 | ABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in children. | 2014 Jul |
1 |
| 24 |
23303573 | Activation of ERM-family proteins via RhoA-ROCK signaling increases intestinal P-gp expression and leads to attenuation of oral morphine analgesia. | 2013 Mar |
2 |
| 25 |
23508810 | Time-dependent changes in the activation of RhoA/ROCK and ERM/p-ERM in the increased expression of intestinal P-glycoprotein by repeated oral treatment with etoposide. | 2013 May |
1 |
| 26 |
23851346 | Cyclosporine-inhibitable blood-brain barrier drug transport influences clinical morphine pharmacodynamics. | 2013 Oct |
2 |
| 27 |
24019224 | Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism. | 2013 Nov |
4 |
| 28 |
22420656 | Etoposide modulates the effects of oral morphine analgesia by targeting the intestinal P-glycoprotein. | 2012 Apr |
3 |
| 29 |
22430884 | Genotypic screening of the main opiate-related polymorphisms in a cohort of 139 sickle cell disease patients. | 2012 May |
1 |
| 30 |
22982667 | RhoA affects oral morphine analgesia depending on functional variation in intestinal P-glycoprotein induced by repeated etoposide treatment. | 2012 Dec 18 |
5 |
| 31 |
23087138 | Decreased analgesic effect of morphine, but not buprenorphine, in patients with advanced P-glycoprotein(+) cancers. | 2012 |
9 |
| 32 |
23226062 | ABCB1 haplotype and OPRM1 118A > G genotype interaction in methadone maintenance treatment pharmacogenetics. | 2012 |
1 |
| 33 |
26019822 | Acute kidney injury in a preterm infant homozygous for the C3435T polymorphism in the ABCB1 gene given oral morphine. | 2012 Oct |
1 |
| 34 |
20932495 | Efflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals. | 2011 May 23 |
1 |
| 35 |
21827411 | Opioid transport by ATP-binding cassette transporters at the blood-brain barrier: implications for neuropsychopharmacology. | 2011 |
2 |
| 36 |
19466410 | Association of UGT2B7 and ABCB1 genotypes with morphine-induced adverse drug reactions in Japanese patients with cancer. | 2010 Jan |
1 |
| 37 |
20627697 | The influence of ATP-binding cassette sub-family B member -1 (ABCB1) genetic polymorphisms on acute and chronic pain after intrathecal morphine for caesarean section: a prospective cohort study. | 2010 Jul |
3 |
| 38 |
19514130 | Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers. | 2009 Jun |
2 |
| 39 |
19721234 | Effects of repeated morphine treatment on the antinociceptive effects, intestinal absorption, and efflux from intestinal epithelial cells of morphine. | 2009 Sep |
2 |
| 40 |
19733628 | Increase in morphine antinociceptive activity by a P-glycoprotein inhibitor in cisplatin-induced neuropathy. | 2009 Nov 6 |
2 |
| 41 |
17722074 | Pharmacogenetics of morphine: Potential implications in sickle cell disease. | 2008 Mar |
1 |
| 42 |
17898703 | Association of ABCB1/MDR1 and OPRM1 gene polymorphisms with morphine pain relief. | 2008 Apr |
5 |
| 43 |
18257092 | Genetic variation and response to morphine in cancer patients: catechol-O-methyltransferase and multidrug resistance-1 gene polymorphisms are associated with central side effects. | 2008 Mar 15 |
2 |
| 44 |
18597654 | Pharmacogenetics of analgesics: toward the individualization of prescription. | 2008 Jul |
6 |
| 45 |
19025521 | Itraconazole, a potent inhibitor of P-glycoprotein, moderately increases plasma concentrations of oral morphine. | 2008 Nov |
3 |
| 46 |
17697052 | Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P-glycoprotein. | 2007 Sep |
2 |
| 47 |
16580900 | Environmental and genetic factors associated with morphine response in the postoperative period. | 2006 Apr |
2 |
| 48 |
16045647 | Genetic variability and clinical efficacy of morphine. | 2005 Aug |
3 |
| 49 |
16215614 | [Genetic variation-- important for the clinical effect of opioids?]. | 2005 Oct 6 |
3 |
| 50 |
15069552 | Effect of short-term morphine exposure on P-glycoprotein expression and activity in cancer cell lines. | 2004 May |
5 |