Daunorubicin

ATP binding cassette subfamily B member 1 ; Homo sapiens







226 Article(s)
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1 34963561 CREB/Sp1-mediated MCL1 expression and NFκB-mediated ABCB1 expression modulate the cytotoxicity of daunorubicin in chronic myeloid leukemia cells. 2022 Jan 15 3
2 34217736 Structure-activity relationship and mechanism of flavonoids on the inhibitory activity of P-glycoprotein (P-gp)-mediated transport of rhodamine123 and daunorubicin in P-gp overexpressed human mouth epidermal carcinoma (KB/MDR) cells. 2021 Sep 3
3 34959345 Effects of Polyphenols on P-Glycoprotein (ABCB1) Activity. 2021 Dec 2 1
4 31290701 Glucosamine Reverses P-Glycoprotein-Mediated Multidrug Resistance in the Daunorubicin-Resistant Human Gastric Cancer Cells. 2020 3
5 31770110 A stress-responsive enhancer induces dynamic drug resistance in acute myeloid leukemia. 2020 Mar 2 2
6 32525004 Tetrandrine enhances glucocorticoid receptor translocation possibly via inhibition of P-glycoprotein in daunorubicin-resistant human T lymphoblastoid leukemia cells. 2020 Aug 15 1
7 33167906 Targeted nanopore sequencing for the identification of ABCB1 promoter translocations in cancer. 2020 Nov 10 1
8 30339824 Modeling drug-drug interactions of AZD1208 with Vincristine and Daunorubicin on ligand-extrusion binding TMD-domains of multidrug resistance P-glycoprotein (ABCB1). 2019 Jan 1 2
9 31035631 Quantitative Structure⁻Activity Relationships for the Flavonoid-Mediated Inhibition of P-Glycoprotein in KB/MDR1 Cells. 2019 Apr 27 2
10 31039321 Confirmation of Selected Synergistic Cancer Drug Combinations Identified in an HTS Campaign and Exploration of Drug Efflux Transporter Contributions to the Mode of Synergy. 2019 Jul 1
11 27865002 Gold(I) NHC Complexes: Antiproliferative Activity, Cellular Uptake, Inhibition of Mammalian and Bacterial Thioredoxin Reductases, and Gram-Positive Directed Antibacterial Effects. 2017 Feb 3 1
12 29016119 9-Deazapurines as Broad-Spectrum Inhibitors of the ABC Transport Proteins P-Glycoprotein, Multidrug Resistance-Associated Protein 1, and Breast Cancer Resistance Protein. 2017 Nov 9 2
13 29070105 [Embelin Reverses the Multi-drug Resistance of K562/D to Daunorubicin Independently of P-gp and MDR1 mRNA]. 2017 Oct 1
14 29079042 ABC-transporter blockage mediated by xanthotoxin and bergapten is the major pathway for chemosensitization of multidrug-resistant cancer cells. 2017 Dec 15 1
15 26836364 Optimization by Molecular Fine Tuning of Dihydro-β-agarofuran Sesquiterpenoids as Reversers of P-Glycoprotein-Mediated Multidrug Resistance. 2016 Mar 10 1
16 27564097 Differential effects of histone deacetylase inhibitors on cellular drug transporters and their implications for using epigenetic modifiers in combination chemotherapy. 2016 Sep 27 1
17 27697501 Deoxycholic acid derivatives as inhibitors of P-glycoprotein-mediated multidrug efflux. 2016 Dec 1
18 25676275 Analysis of the impact of extracellular acidity on the expression and activity of P-glycoprotein and on the P-glycoprotein-mediated cytotoxicity of daunorubicin in cancer cell by microfluidic chip technology. 2015 Feb 2
19 25695368 Restoration of Chemosensitivity in P-Glycoprotein-Dependent Multidrug-Resistant Cells by Dihydro-β-agarofuran Sesquiterpenes from Celastrus vulcanicola. 2015 Apr 24 1
20 25776492 Effects of natural nuclear factor-kappa B inhibitors on anticancer drug efflux transporter human P-glycoprotein. 2015 Mar 2
21 26125482 Multiple Drug Transport Pathways through Human P-Glycoprotein. 2015 Jul 21 1
22 24595806 Folates provoke cellular efflux and drug resistance of substrates of the multidrug resistance protein 1 (MRP1). 2014 May 3
23 24903378 In vitro antileukaemic activity of extracts from Daphne gnidium leaves against sensitive and multidrug resistant K562/R7 cells. 2014 Sep 1
24 24954033 Resistance to daunorubicin, imatinib, or nilotinib depends on expression levels of ABCB1 and ABCG2 in human leukemia cells. 2014 Aug 5 1
25 23103446 Can P-glycoprotein mediate resistance to nilotinib in human leukaemia cells? 2013 Jan 1
26 23400406 2D- and 3D-QSAR studies of a series of benzopyranes and benzopyrano[3,4b][1,4]-oxazines as inhibitors of the multidrug transporter P-glycoprotein. 2013 Feb 1
27 24062304 P-glycoprotein mediates drug resistance via a novel mechanism involving lysosomal sequestration. 2013 Nov 1 1
28 24376706 Purvalanol A, olomoucine II and roscovitine inhibit ABCB1 transporter and synergistically potentiate cytotoxic effects of daunorubicin in vitro. 2013 7
29 22145750 Proteasome inhibitor bortezomib overcomes P-gp-mediated multidrug resistance in resistant leukemic cell lines. 2012 Jun 1
30 22868178 Progesterone-adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux: design, synthesis, characterization and biological evaluation. 2012 Oct 1
31 21287651 Different transport activity of human triallelic MDR1 893Ala/Ser/Thr variant and its association with herb extracts. 2011 Aug 1
32 21591994 Amonafide: a potential role in treating acute myeloid leukemia. 2011 Jul 1
33 21641880 Assay for determination of daunorubicin in cancer cells with multidrug resistance phenotype. 2011 Jul 1 2
34 21679421 P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the aurora-B kinase inhibitor barasertib-hQPA. 2011 Jun 16 1
35 19763573 PSC833, cyclosporine analogue, downregulates MDR1 expression by activating JNK/c-Jun/AP-1 and suppressing NF-kappaB. 2010 May 1
36 20185911 Effects of iron deprivation on multidrug resistance of leukemic K562 cells. 2010 1
37 20335952 Quercetin as a potential modulator of P-glycoprotein expression and function in cells of human pancreatic carcinoma line resistant to daunorubicin. 2010 Feb 9 1
38 20399647 Design, synthesis and evaluation of progesterone-adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux. 2010 May 15 1
39 20642825 Functional study of the novel multidrug resistance gene HA117 and its comparison to multidrug resistance gene 1. 2010 Jul 19 1
40 20682982 Iodination increases the activity of verapamil derivatives in reversing PGP multidrug resistance. 2010 Jul 1
41 22069634 Overcoming multidrug resistance in human cancer cells by natural compounds. 2010 Jun 1
42 18440836 P-glycoprotein activity in renal clear cell carcinoma. 2009 Jul-Aug 2
43 18924151 The pH sensitive probe 5-(and-6)-carboxyl seminaphthorhodafluor is a substrate for the multidrug resistance-related protein MRP1. 2009 Jan 1 1
44 18972190 Impact of novel MDR modulators on human cancer cells: reversal activities and induction studies. 2009 Jan 1
45 19108889 A phase I trial of continuous infusion of the multidrug resistance inhibitor zosuquidar with daunorubicin and cytarabine in acute myeloid leukemia. 2009 Aug 1
46 19777523 Activators of P-glycoprotein: Structure-activity relationships and investigation of their mode of action. 2009 Nov 1
47 20024113 Novel dihydro-beta-agarofuran sesquiterpenes as potent modulators of human P-glycoprotein dependent multidrug resistance. 2009 Dec 21 1
48 18204840 Inhibition of P-glycoprotein and multidrug resistance protein 1 by dietary phytochemicals. 2008 Oct 1
49 18249061 MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia. 2008 Apr 1
50 18280247 Effects of plant sterols on human multidrug transporters ABCB1 and ABCC1. 2008 May 2 1