| 1 |
33858315 | Evaluation of Benzamide-Chalcone Derivatives as EGFR/CDK2 Inhibitor: Synthesis, In-Vitro Inhibition, and Molecular Modeling Studies. | 2022 |
1 |
| 2 |
34097593 | Efficient Synthesis and Biological Evaluation of 6-Trifluoroethoxy Functionalized Pteridine Derivatives as EGFR Inhibitors. | 2022 |
1 |
| 3 |
34633106 | A novel cyclic NP1 reveals obstruction of EGFR kinase activity and attenuation of EGFR-driven cell lines. | 2022 Feb |
1 |
| 4 |
35129191 | Polyphenol-modified nanovesicles for synergistically enhanced in vitro tumor cell targeting and apoptosis. | 2022 Mar 9 |
1 |
| 5 |
35178955 | [Mechanism of polyphyllin Ⅰ targeting EGFR to affect proliferation and apoptosis of human breast cancer cells]. | 2022 Feb |
1 |
| 6 |
35381900 | In silico approach to probe the binding affinity between OMVs harboring the ZEGFR affibody and the EGF receptor. | 2022 Apr 5 |
1 |
| 7 |
35578853 | Automated In silico EGFR Peptide Inhibitor Elongation Using Self-Evolving Peptide Algorithm. | 2022 May 16 |
1 |
| 8 |
32698735 | Design, Synthesis, In Silico and In Vitro Evaluation of Novel Pyrimidine Derivatives as EGFR Inhibitors. | 2021 |
2 |
| 9 |
33161110 | Cucurbitacin IIb induces apoptosis and cell cycle arrest through regulating EGFR/MAPK pathway. | 2021 Jan |
1 |
| 10 |
34271119 | Inhibitory activities of 20(R, S)-protopanaxatriol against epidermal growth factor receptor tyrosine kinase. | 2021 Sep |
1 |
| 11 |
30652647 | Computational Studies of bis-2-Oxoindoline Succinohydrazides and their In Vitro Cytotoxicity. | 2020 |
1 |
| 12 |
31787359 | Discovery of novel 9-heterocyclyl substituted 9H-purines as L858R/T790M/C797S mutant EGFR tyrosine kinase inhibitors. | 2020 Jan 15 |
1 |
| 13 |
32139324 | Design and synthesis of a novel class EGFR/HER2 dual inhibitors containing tricyclic oxazine fused quinazolines scaffold. | 2020 May 1 |
1 |
| 14 |
32440336 | Silver(I) metallodrugs of thiosemicarbazones and naproxen: biocompatibility, in vitro anti-proliferative activity and in silico interaction studies with EGFR, VEGFR2 and LOX receptors. | 2020 Feb |
1 |
| 15 |
32653374 | Kinetic and thermodynamic insights into interaction of erlotinib with epidermal growth factor receptor: Surface plasmon resonance and molecular docking approaches. | 2020 Nov 15 |
1 |
| 16 |
33096664 | Ligand-Based Pharmacophore Modeling, Molecular Docking, and Molecular Dynamic Studies of Dual Tyrosine Kinase Inhibitor of EGFR and VEGFR2. | 2020 Oct 21 |
1 |
| 17 |
33374155 | Discovery of Potent Dual EGFR/HER2 Inhibitors Based on Thiophene Scaffold Targeting H1299 Lung Cancer Cell Line. | 2020 Dec 24 |
1 |
| 18 |
30593826 | Hydrogen bond analysis of the EGFR-ErbB3 heterodimer related to non-small cell lung cancer and drug resistance. | 2019 Mar 7 |
1 |
| 19 |
30716685 | Molecular dynamic investigate the affection of EGFR by Tubemoside. | 2019 May |
1 |
| 20 |
31223050 | QSAR modeling, pharmacophore-based virtual screening, and ensemble docking insights into predicting potential epigallocatechin gallate (EGCG) analogs against epidermal growth factor receptor. | 2019 Feb |
1 |
| 21 |
31241919 | Biocompatibility, in Vitro Antiproliferative, and in Silico EGFR/VEGFR2 Studies of Heteroleptic Metal(II) Complexes of Thiosemicarbazones and Naproxen. | 2019 Aug 19 |
1 |
| 22 |
31536605 | Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation. | 2019 |
3 |
| 23 |
31710991 | In silico design, synthesis and activity of potential drug-like chrysin scaffold-derived selective EGFR inhibitors as anticancer agents. | 2019 Dec |
1 |
| 24 |
29207336 | Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones. | 2018 Jan 1 |
1 |
| 25 |
29363191 | Investigation of the binding characteristics between ligands and epidermal growth factor receptor by cell membrane chromatography. | 2018 Jun |
1 |
| 26 |
29421573 | 6,7-Dimorpholinoalkoxy quinazoline derivatives as potent EGFR inhibitors with enhanced antiproliferative activities against tumor cells. | 2018 Mar 10 |
1 |
| 27 |
29462206 | Cell-free synthesis of functional antibody fragments to provide a structural basis for antibody-antigen interaction. | 2018 |
1 |
| 28 |
29466773 | Discovery of 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as new EGFR-TKIs. | 2018 Mar 25 |
1 |
| 29 |
29571113 | Synthesis of stable benzimidazole derivatives bearing pyrazole as anticancer and EGFR receptor inhibitors. | 2018 Aug |
1 |
| 30 |
30607149 | Exploring the interaction between epidermal growth factor receptor tyrosine kinase and some of the synthesized inhibitors using combination of in-silico and in-vitro cytotoxicity methods. | 2018 Dec |
2 |
| 31 |
27691399 | Affinity enhancement of nanobody binding to EGFR: in silico site-directed mutagenesis and molecular dynamics simulation approaches. | 2017 Jun |
1 |
| 32 |
28290719 | Molecular dynamics and pharmacophore modelling studies of different subtype (ALK and EGFR (T790M)) inhibitors in NSCLC. | 2017 Mar |
3 |
| 33 |
28482570 | Heteroleptic silver(I) complexes with 2,2':6',2″-terpyridines and naproxen: DNA interaction, EGFR/VEGFR2 kinase, growth inhibition and cell cycle arrest studies. | 2017 Jul 1 |
1 |
| 34 |
26096169 | Mapping inhibitor response to the in-frame deletions, insertions and duplications of epidermal growth factor receptor (EGFR) in non-small cell lung cancer. | 2016 |
2 |
| 35 |
26763193 | Synthesis of p-O-Alkyl Salicylanilide Derivatives as Novel EGFR Inhibitors. | 2016 Feb |
1 |
| 36 |
27524310 | Synthesis and biological evaluation of novel tricyclic oxazine and oxazepine fused quinazolines. Part 2: Gefitinib analogs. | 2016 Oct 1 |
1 |
| 37 |
24954438 | Synthesis and evaluation of salicylanilide derivatives as potential epidermal growth factor receptor inhibitors. | 2015 Mar |
1 |
| 38 |
25175686 | Design, synthesis and biological evaluation of quinoxalin-2(1H)-one derivatives as EGFR tyrosine kinase inhibitors. | 2015 |
1 |
| 39 |
26629323 | JAK3 inhibitor VI is a mutant specific inhibitor for epidermal growth factor receptor with the gatekeeper mutation T790M. | 2015 Nov 26 |
1 |
| 40 |
24269511 | Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors. | 2014 Jan |
1 |
| 41 |
24411123 | Synthesis and biological evaluation of novel tricyclic oxazine and oxazepine fused quinazolines. Part 1: erlotinib analogs. | 2014 Feb 1 |
1 |
| 42 |
24607998 | Design, synthesis and molecular modeling of pyrazole-quinoline-pyridine hybrids as a new class of antimicrobial and anticancer agents. | 2014 Apr 9 |
2 |
| 43 |
24853453 | Synthesis, molecular docking and biological evaluation of glycyrrhizin analogs as anticancer agents targeting EGFR. | 2014 May 19 |
2 |
| 44 |
25172421 | Design, synthesis and molecular modeling of biquinoline-pyridine hybrids as a new class of potential EGFR and HER-2 kinase inhibitors. | 2014 Sep 15 |
1 |
| 45 |
25305687 | Optimization of gefitinib analogues with potent anticancer activity. | 2014 Nov 15 |
1 |
| 46 |
23490150 | Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors. | 2013 Apr 15 |
1 |
| 47 |
23538097 | On the nanotoxicity of PAMAM dendrimers: Superfect® stimulates the EGFR-ERK1/2 signal transduction pathway via an oxidative stress-dependent mechanism in HEK 293 cells. | 2013 May 1 |
1 |
| 48 |
22414612 | Synthesis and evaluation of 1-(substituted)-3-prop-2-ynylureas as antiangiogenic agents. | 2012 Apr 15 |
2 |
| 49 |
22486613 | Targeting the epidermal growth factor receptor: exploring the potential of novel inhibitor N-(3-ethynylphenyl)-6, 7-bis (2-methoxyethoxy) quinolin- 4-amine using docking and molecular dynamics simulation. | 2012 Sep |
1 |
| 50 |
21426301 | Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases. | 2011 Jun 1 |
1 |