epigallocatechin gallate

epidermal growth factor receptor ; Homo sapiens







56 Article(s)
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1 35063850 Epigallocatechin 3-gallate: From green tea to cancer therapeutics. 2022 Jun 15 1
2 35211881 The Efficacy Mechanism of Epigallocatechin Gallate against Pre-Eclampsia based on Network Pharmacology and Molecular Docking. 2022 Jun 1
3 33587351 Proliferation of MDA-MB-231 can be suppressed by dimeric-epigallocatechin gallate through competitive inhibition of amphiregulin-epidermal growth factor receptor signaling. 2021 Jun 1 7
4 34299635 Novel Perbutyrylated Glucose Derivatives of (-)-Epigallocatechin-3-Gallate Inhibit Cancer Cells Proliferation by Decreasing Phosphorylation of the EGFR: Synthesis, Cytotoxicity, and Molecular Docking. 2021 Jul 19 2
5 34769263 Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer. 2021 Oct 31 5
6 31979082 Preclinical Pharmacological Activities of Epigallocatechin-3-gallate in Signaling Pathways: An Update on Cancer. 2020 Jan 22 2
7 32138321 Conformational Insight on WT- and Mutated-EGFR Receptor Activation and Inhibition by Epigallocatechin-3-Gallate: Over a Rational Basis for the Design of Selective Non-Small-Cell Lung Anticancer Agents. 2020 Mar 3 1
8 32217102 The inhibitory effect of ECG and EGCG dimeric procyanidins on colorectal cancer cells growth is associated with their actions at lipid rafts and the inhibition of the epidermal growth factor receptor signaling. 2020 May 10
9 30858760 Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway. 2019 4
10 31188490 Functional and molecular effects of a green tea constituent on oral cancer cells. 2019 Aug 4
11 31223050 QSAR modeling, pharmacophore-based virtual screening, and ensemble docking insights into predicting potential epigallocatechin gallate (EGCG) analogs against epidermal growth factor receptor. 2019 Feb 9
12 31934166 ERα36 is an effective target of epigallocatechin-3-gallate in hepatocellular carcinoma. 2019 1
13 29157036 Epigallocatechin-3-O-gallate alleviates the malignant phenotype in A-431 epidermoid and SK-BR-3 breast cancer cell lines. 2018 Aug 2
14 29329808 Structural and energetic basis for the molecular recognition of dual synthetic vs. natural inhibitors of EGFR/HER2. 2018 May 1
15 28247504 Epigallocatechin-3-gallate augments the therapeutic effects of benzo[a]pyrene-mediated lung carcinogenesis. 2017 Jul 8 2
16 28286519 ErbB Proteins as Molecular Target of Dietary Phytochemicals in Malignant Diseases. 2017 1
17 28432554 Epigallocatechin gallate protects BEAS-2B cells from lipopolysaccharide-induced apoptosis through upregulation of gastrin-releasing peptide. 2017 Oct 2
18 28465354 EGFR inhibition by (-)-epigallocatechin-3-gallate and IIF treatments reduces breast cancer cell invasion. 2017 Jun 30 3
19 28485162 Epigallocatechin gallate inhibits the growth of salivary adenoid cystic carcinoma cells via the EGFR/Erk signal transduction pathway and the mitochondria apoptosis pathway. 2017 3
20 28487468 Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains. 2017 Jun 16 3
21 29276223 Effects of (-)-epigallocatechin-3-gallate on EGFR- or Fusion Gene-driven Lung Cancer Cells. 2017 Dec 1
22 25591943 Epigallocatechin gallate inhibits human tongue carcinoma cells via HK2‑mediated glycolysis. 2015 Mar 4
23 25860284 Combination of erlotinib and EGCG induces apoptosis of head and neck cancers through posttranscriptional regulation of Bim and Bcl-2. 2015 Jul 1
24 26077136 Anchor-based classification and type-C inhibitors for tyrosine kinases. 2015 Jun 16 1
25 24366444 Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway. 2014 Mar 10
26 24456004 Epigallocatechin 3-O-gallate induces 67 kDa laminin receptor-mediated cell death accompanied by downregulation of ErbB proteins and altered lipid raft clustering in mammary and epidermoid carcinoma cells. 2014 Feb 28 1
27 24508477 Curcumin and (-)-epigallocatechin-3-gallate attenuate acrylamide-induced proliferation in HepG2 cells. 2014 Apr 1
28 24798568 Copolymeric micelles for delivery of EGCG and cyclopamine to pancreatic cancer cells. 2014 1
29 25263976 Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent activation of extracellular signal-regulated kinase 1/2 in Jurkat cells. 2014 Sep 1
30 22769244 Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer. 2012 Jul 6 3
31 22923287 Epigallocatechin gallate sensitizes CAL-27 human oral squamous cell carcinoma cells to the anti-metastatic effects of gefitinib (Iressa) via synergistic suppression of epidermal growth factor receptor and matrix metalloproteinase-2. 2012 Nov 4
32 20446926 (-)-Epigallocatechin-3-gallate down-regulates EGFR, MMP-2, MMP-9 and EMMPRIN and inhibits the invasion of MCF-7 tamoxifen-resistant cells. 2011 Apr 6
33 21391127 The effect of green tea extract and EGCG on the signaling network in squamous cell carcinoma. 2011 2
34 21538846 Cancer chemoprevention with green tea catechins by targeting receptor tyrosine kinases. 2011 Jun 5
35 21725973 Epigallocatechin-3-gallate induces growth inhibition and apoptosis of human anaplastic thyroid carcinoma cells through suppression of EGFR/ERK pathway and cyclin B1/CDK1 complex. 2011 Dec 4
36 19578043 (-)-Epigallocatechin gallate downregulates EGF receptor via phosphorylation at Ser1046/1047 by p38 MAPK in colon cancer cells. 2009 Sep 14
37 18586691 (-)-Epigallocatechin gallate causes internalization of the epidermal growth factor receptor in human colon cancer cells. 2008 Oct 8
38 18618485 Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation. 2008 Jul 1
39 19261982 Molecular targets of (-)-epigallocatechin-3-gallate (EGCG): specificity and interaction with membrane lipid rafts. 2008 Dec 3
40 19325845 Targeting receptor tyrosine kinases for chemoprevention by green tea catechin, EGCG. 2008 Jun 3
41 17539658 Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling. 2007 Jun 27 5
42 17569617 Green tea polyphenols: biology and therapeutic implications in cancer. 2007 Sep 1 1
43 17616711 The inhibitory effect of (-)-epigallocatechin gallate on activation of the epidermal growth factor receptor is associated with altered lipid order in HT29 colon cancer cells. 2007 Jul 1 8
44 16404708 Mechanisms of hypolipidemic and anti-obesity effects of tea and tea polyphenols. 2006 Feb 1
45 15814656 (-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells. 2005 Apr 1 7
46 16053920 EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells. 2005 Sep 2 1
47 16140980 Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells. 2005 Sep 1 8
48 16416603 EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells. 2005 4
49 14701854 Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases. 2004 Mar 26 5
50 15147726 Interference effect of epigallocatechin-3-gallate on targets of nuclear factor kappaB signal transduction pathways activated by EB virus encoded latent membrane protein 1. 2004 Aug 3