Oxygen

AKT serine/threonine kinase 1 ; Homo sapiens







67 Article(s)
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1 34979107 Adapted suspension tumor cells rewire metabolic pathways for anchorage-independent survival through AKT activation. 2022 Feb 15 1
2 35072776 miR-193a-3p increases glycolysis under hypoxia by facilitating Akt phosphorylation and PFKFB3 activation in human macrophages. 2022 Jan 24 1
3 35385843 Stress, Thyroid Dysregulation and Thyroid Cancer in Children and Adolescents. Proposed Impending Mechanisms. 2022 Apr 6 1
4 33278780 Altered glucose metabolism and cell function in keloid fibroblasts under hypoxia. 2021 Jan 1
5 33642395 Exosomes derived from human induced pluripotent stem cell-derived neural progenitor cells protect neuronal function under ischemic conditions. 2021 Oct 1
6 33785835 In oxygen-deprived tumor cells ERp57 provides radioprotection and ensures proliferation via c-Myc, PLK1 and the AKT pathway. 2021 Mar 30 1
7 34293347 Rac-dependent feedforward autoactivation of NOX2 leads to oxidative burst. 2021 Aug 2
8 31648572 Radiosensitizing Potential of Curcumin in Different Cancer Models. 2020 1
9 31870893 MiR-340-5p alleviates oxygen-glucose deprivation/reoxygenation-induced neuronal injury via PI3K/Akt activation by targeting PDCD4. 2020 Mar 1
10 31991669 Curcumin-Loaded Solid Lipid Nanoparticles Bypass P-Glycoprotein Mediated Doxorubicin Resistance in Triple Negative Breast Cancer Cells. 2020 Jan 24 1
11 32043704 Repression of Kisspeptin1 weakens hydrogen peroxide-caused injury in HTR8 cells via adjusting PI3K/AKT/mTOR pathway. 2020 May 1
12 32691710 Tumor-Induced Metabolism and T Cells Located in Tumor Environment. 2020 1
13 32802113 In Vitro Evaluation of the Neuroprotective Effect of Panax notoginseng Saponins by Activating the EGFR/PI3K/AKT Pathway. 2020 1
14 33101583 Reactive Oxygen Species Induce Endothelial Differentiation of Liver Cancer Stem-Like Sphere Cells through the Activation of Akt/IKK Signaling Pathway. 2020 1
15 33283112 The Inhibition of H1N1 Influenza Virus-Induced Apoptosis by Surface Decoration of Selenium Nanoparticles with β-Thujaplicin through Reactive Oxygen Species-Mediated AKT and p53 Signaling Pathways. 2020 Dec 1 1
16 33553145 Both Hypoxia-Inducible Factor 1 and MAPK Signaling Pathway Attenuate PI3K/AKT via Suppression of Reactive Oxygen Species in Human Pluripotent Stem Cells. 2020 1
17 30535469 PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review). 2019 Feb 1
18 31108306 Chronic mild stress leads to aberrant glucose energy metabolism in depressed Macaca fascicularis models. 2019 Sep 1
19 31673096 Mitochondria damaged by Oxygen Glucose Deprivation can be Restored through Activation of the PI3K/Akt Pathway and Inhibition of Calcium Influx by Amlodipine Camsylate. 2019 Oct 31 1
20 31680961 Piperlongumine Inhibits Akt Phosphorylation to Reverse Resistance to Cisplatin in Human Non-Small Cell Lung Cancer Cells via ROS Regulation. 2019 1
21 31814867 Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide. 2019 1
22 31885775 CGRP Reduces Apoptosis of DRG Cells Induced by High-Glucose Oxidative Stress Injury through PI3K/AKT Induction of Heme Oxygenase-1 and Nrf-2 Expression. 2019 1
23 29318974 Understanding the Role of Hypoxia Inducible Factor During Neurodegeneration for New Therapeutics Opportunities. 2018 1
24 29523748 High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2. 2018 Apr 5 1
25 29908183 MIF protects against oxygen-glucose deprivation-induced ototoxicity in HEI-OC1 cochlear cells by enhancement of Akt-Nrf2-HO-1 pathway. 2018 Sep 5 1
26 30223019 VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC. 2018 Dec 1
27 27772541 Bone Marrow Stromal Cells Combined With Sodium Ferulate and n-Butylidenephthalide Promote the Effect of Therapeutic Angiogenesis via Advancing Astrocyte-Derived Trophic Factors After Ischemic Stroke. 2017 Feb 16 1
28 28146458 Moderate hyperoxia induces inflammation, apoptosis and necrosis in human umbilical vein endothelial cells: An in-vitro study. 2017 Mar 1
29 28348480 Ghrelin and gastrointestinal stromal tumors. 2017 Mar 14 1
30 28838128 Hypoxia Sensing in Plants: On a Quest for Ion Channels as Putative Oxygen Sensors. 2017 Jul 1 1
31 28886081 Orexin A affects HepG2 human hepatocellular carcinoma cells glucose metabolism via HIF-1α-dependent and -independent mechanism. 2017 1
32 26760116 Low Oxygen Tension Modulates the Insulin-Like Growth Factor-1 or -2 Signaling via Both Insulin-Like Growth Factor-1 Receptor and Insulin Receptor to Maintain Stem Cell Identity in Placental Mesenchymal Stem Cells. 2016 Mar 1
33 27059084 Low Oxygen Modulates Multiple Signaling Pathways, Increasing Self-Renewal, While Decreasing Differentiation, Senescence, and Apoptosis in Stromal MIAMI Cells. 2016 Jun 1 3
34 27563096 pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner. 2016 Aug 26 2
35 25348671 Oct-3/4 promotes tumor angiogenesis through VEGF production in glioblastoma. 2015 Jan 1
36 25995437 The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1α Phosphorylation. 2015 Aug 2
37 26366999 IL-10 Protects Neurites in Oxygen-Glucose-Deprived Cortical Neurons through the PI3K/Akt Pathway. 2015 2
38 24504963 Cell-free NADPH oxidase activation assays: "in vitro veritas". 2014 1
39 24506070 Low-oxygen tension and IGF-I promote proliferation and multipotency of placental mesenchymal stem cells (PMSCs) from different gestations via distinct signaling pathways. 2014 Apr 1
40 23297826 Oxygen-independent regulation of HIF-1: novel involvement of PI3K/AKT/mTOR pathway in cancer. 2013 Mar 1
41 23336598 Human umbilical cord blood mononuclear cell-conditioned media inhibits hypoxic-induced apoptosis in human coronary artery endothelial cells and cardiac myocytes by activation of the survival protein Akt. 2013 2
42 23671091 Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids. 2013 May 28 1
43 22652785 The expression and regulation of aquaporins in placenta and fetal membranes. 2012 Jun 1 1
44 21265612 The pivotal role of reactive oxygen species generation in the hypoxia-induced stimulation of adipose-derived stem cells. 2011 Oct 1
45 21555366 Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. 2011 Jul 1 2
46 20037603 HIF-1alpha links beta-adrenoceptor agonists and pancreatic cancer cells under normoxic condition. 2010 Jan 1
47 20153226 A comprehensive structure-activity analysis of protein kinase B-alpha (Akt1) inhibitors. 2010 Apr 1
48 20497028 Hyperbaric oxygen-stimulated proliferation and growth of osteoblasts may be mediated through the FGF-2/MEK/ERK 1/2/NF-κB and PKC/JNK pathways. 2010 Dec 1
49 18781596 Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway. 2009 Jan 1
50 19098000 The Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors. 2009 Feb 20 1