Cisplatin

transformation related protein 53, pseudogene ; Mus musculus







121 Article(s)
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1 35203361 p53 in Proximal Tubules Mediates Chronic Kidney Problems after Cisplatin Treatment. 2022 Feb 17 2
2 35456022 Apoptotic and DNA Damage Effect of 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose in Cisplatin-Resistant Non-Small Lung Cancer Cells via Phosphorylation of H2AX, CHK2 and p53. 2022 Apr 14 1
3 35468881 JMJD2C mediates the MDM2/p53/IL5RA axis to promote CDDP resistance in uveal melanoma. 2022 Apr 25 4
4 32860126 Quercetin attenuates cisplatin-induced fat loss. 2021 Jun 1
5 33646450 PPAR-δ activation reduces cisplatin-induced apoptosis via inhibiting p53/Bax/caspase-3 pathway without modulating autophagy in murine renal proximal tubular cells. 2021 Jun 1
6 33722665 NAM protects against cisplatin-induced acute kidney injury by suppressing the PARP1/p53 pathway. 2021 May 1 4
7 34461812 Protective Effect of 20(R)-Ginsenoside Rg3 Against Cisplatin-Induced Renal Toxicity via PI3K/AKT and NF-[Formula: see text]B Signaling Pathways Based on the Premise of Ensuring Anticancer Effect. 2021 1
8 33086658 The Role of GDF15 in Regulating the Canonical Pathways of the Tumor Microenvironment in Wild-Type p53 Ovarian Tumor and Its Response to Chemotherapy. 2020 Oct 19 2
9 33103444 AMP-activated protein kinase contributes to cisplatin-induced renal epithelial cell apoptosis and acute kidney injury. 2020 Dec 1 5
10 33230463 TNFAIP8 Promotes Cisplatin Chemoresistance in Triple-Negative Breast Cancer by Repressing p53-Mediated miR-205-5p Expression. 2020 Dec 4 1
11 33327548 Inhibition of p300 by Garcinol Protects against Cisplatin-Induced Acute Kidney Injury through Suppression of Oxidative Stress, Inflammation, and Tubular Cell Death in Mice. 2020 Dec 14 1
12 30797149 Renoprotective effect of scutellarin on cisplatin-induced renal injury in mice: Impact on inflammation, apoptosis, and autophagy. 2019 Apr 1
13 31148231 p53 induces miR-199a-3p to suppress mechanistic target of rapamycin activation in cisplatin-induced acute kidney injury. 2019 Oct 1
14 31726654 Salvianolic Acid B Slows the Progression of Breast Cancer Cell Growth via Enhancement of Apoptosis and Reduction of Oxidative Stress, Inflammation, and Angiogenesis. 2019 Nov 12 1
15 29223537 RANKL Signaling Sustains Primary Tumor Growth in Genetically Engineered Mouse Models of Lung Adenocarcinoma. 2018 Mar 1
16 29276099 Lethal (3) malignant brain tumor-like 2 (L3MBTL2) protein protects against kidney injury by inhibiting the DNA damage-p53-apoptosis pathway in renal tubular cells. 2018 Apr 2
17 29401620 FGF21 is induced in cisplatin nephrotoxicity to protect against kidney tubular cell injury. 2018 Jun 1
18 29449532 Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway. 2018 Feb 15 1
19 29760794 Yangyin Fuzheng Decoction enhances anti-tumor efficacy of cisplatin on lung cancer. 2018 1
20 29767555 Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity. 2018 Sep 1 1
21 27550999 Therapeutic Inhibition of the MDM2-p53 Interaction Prevents Recurrence of Adenoid Cystic Carcinomas. 2017 Feb 15 1
22 27895157 Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI. 2017 May 2
23 28224201 Dexmedetomidine protects against cisplatin-induced acute kidney injury in mice through regulating apoptosis and inflammation. 2017 May 1
24 28414026 Targeting Oct2 and P53: Formononetin prevents cisplatin-induced acute kidney injury. 2017 Jul 1 1
25 28440085 Actinomycin D synergistically enhances the cytotoxicity of CDDP on KB cells by activating P53 via decreasing P53-MDM2 complex. 2017 Jun 2
26 28912139 A Combination RNAi-Chemotherapy Layer-by-Layer Nanoparticle for Systemic Targeting of KRAS/P53 with Cisplatin to Treat Non-Small Cell Lung Cancer. 2017 Dec 1 1
27 29262553 Inhibition of PTEN activity aggravates cisplatin-induced acute kidney injury. 2017 Nov 28 2
28 29340044 Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals. 2017 Dec 19 1
29 27484725 Co-expression of ING4 and P53 enhances hypopharyngeal cancer chemosensitivity to cisplatin in vivo. 2016 Sep 1
30 27721894 The Fruit Hull of Gleditsia sinensis Enhances the Anti-Tumor Effect of cis-Diammine Dichloridoplatinum II (Cisplatin). 2016 1
31 25730340 Sensitization of cisplatin therapy by a naphthalimide based organoselenium compound through modulation of antioxidant enzymes and p53 mediated apoptosis. 2015 Apr 1
32 25875356 Mitochondrial modulation by Epigallocatechin 3-Gallate ameliorates cisplatin induced renal injury through decreasing oxidative/nitrative stress, inflammation and NF-kB in mice. 2015 1
33 26019260 Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice. 2015 Jul 3
34 26366090 Apoptotic effect of cordycepin combined with cisplatin and/or paclitaxel on MA-10 mouse Leydig tumor cells. 2015 2
35 26431211 P53 Contributes to Cisplatin Induced Renal Oxidative Damage via Regulating P66shc and MnSOD. 2015 6
36 24115477 UNC5B receptor deletion exacerbates tissue injury in response to AKI. 2014 Feb 1
37 24522076 Re: enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated salmonella carrying a plasmid co-expressing p53 gene and MDM2 siRNA. 2014 Mar 1
38 24595063 Vasohibin 2 decreases the cisplatin sensitivity of hepatocarcinoma cell line by downregulating p53. 2014 1
39 24621580 Proteomics analysis of normal and senescent NG108-15 cells: GRP78 plays a negative role in cisplatin-induced senescence in the NG108-15 cell line. 2014 1
40 24700871 Tubular p53 regulates multiple genes to mediate AKI. 2014 Oct 1
41 24759152 Discovery of an integrative network of microRNAs and transcriptomics changes for acute kidney injury. 2014 Nov 2
42 24916697 Cisplatin-induced renal injury is independently mediated by OCT2 and p53. 2014 Aug 1 3
43 24933647 Anti-cancer effects of ursane triterpenoid as a single agent and in combination with cisplatin in bladder cancer. 2014 Oct 5 1
44 25308879 P2X7 receptor blockade protects against cisplatin-induced nephrotoxicity in mice by decreasing the activities of inflammasome components, oxidative stress and caspase-3. 2014 Nov 15 1
45 22674879 Molecular imaging of p53 signal pathway in lung cancer cell cycle arrest induced by cisplatin. 2013 Nov 8
46 23515721 Basic helix-loop-helix transcriptional factor MyoR regulates BMP-7 in acute kidney injury. 2013 May 1 1
47 23660976 Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicity. 2013 Jul 3
48 23726840 Enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated Salmonella carrying a plasmid co-expressing p53 gene and mdm2 siRNA. 2013 Aug 28 3
49 23873478 The role of p53 in combination radioimmunotherapy with 64Cu-DOTA-cetuximab and cisplatin in a mouse model of colorectal cancer. 2013 Sep 3
50 24176857 miR-125b transcriptionally increased by Nrf2 inhibits AhR repressor, which protects kidney from cisplatin-induced injury. 2013 Oct 31 1