2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

tumor protein p53 ; Homo sapiens







32 Article(s)
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1 28287251 Cisplatin induced apoptosis of ovarian cancer A2780s cells by activation of ERK/p53/PUMA signals. 2018 Jan 1
2 28833404 Suppression of c-Myc enhances p21WAF1/CIP1 -mediated G1 cell cycle arrest through the modulation of ERK phosphorylation by ascochlorin. 2018 Feb 1
3 29405768 Diepoxybutane-induced apoptosis is mediated through the ERK1/2 pathway. 2018 Oct 2
4 28785074 Low dose arsenite confers resistance to UV induced apoptosis via p53-MDM2 pathway in ketatinocytes. 2017 Aug 7 1
5 26497030 The Ras/Raf/Erk Pathway Mediates the Subarachnoid Hemorrhage-Induced Apoptosis of Hippocampal Neurons Through Phosphorylation of p53. 2016 Oct 3
6 26386653 Mechanisms involved in p53 downregulation by leptin in trophoblastic cells. 2015 Nov 1
7 22466960 Activation of ERK-p53 and ERK-mediated phosphorylation of Bcl-2 are involved in autophagic cell death induced by the c-Met inhibitor SU11274 in human lung cancer A549 cells. 2012 1
8 21261644 Resveratrol and apoptosis. 2011 Jan 1
9 20036733 Photoinflammatory responses to UV-irradiated ketoprofen mediated by the induction of ROS generation, enhancement of cyclooxygenase-2 expression, and regulation of multiple signaling pathways. 2010 Mar 15 1
10 20564491 Gleditsia sinensis thorn extract inhibits human colon cancer cells: the role of ERK1/2, G2/M-phase cell cycle arrest and p53 expression. 2010 Dec 1
11 21311676 Melatonin Induces Apoptotic Cell Death via p53 in LNCaP Cells. 2010 Dec 1
12 18406507 MAPK regulate p53-dependent cell death induced by benzo[a]pyrene: involvement of p53 phosphorylation and acetylation. 2008 May 21 2
13 17409429 Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells. 2007 Apr 1 6
14 16180010 Involvement of the extracellular signal-regulated protein kinase pathway in phosphorylation of p53 protein and exerting cytotoxicity in human neuroblastoma cells (SH-SY5Y) exposed to acrylamide. 2006 Mar 1
15 16527552 Activation of Akt and ERK signalling pathways induced by etoposide confer chemoresistance in gastric cancer cells. 2006 May 1
16 16814113 Potent antiproliferative effects of resveratrol on human osteosarcoma SJSA1 cells: Novel cellular mechanisms involving the ERKs/p53 cascade. 2006 Jul 15 1
17 16840547 S179D prolactin primarily uses the extrinsic pathway and mitogen-activated protein kinase signaling to induce apoptosis in human endothelial cells. 2006 Oct 1
18 16880619 The course of uncarinic acid E-induced apoptosis of HepG2 cells from damage to DNA and p53 activation to mitochondrial release of cytochrome c. 2006 Aug 1
19 16928824 Resveratrol-induced cyclooxygenase-2 facilitates p53-dependent apoptosis in human breast cancer cells. 2006 Aug 1
20 15880691 Inhibition of extracellular signal regulated kinase (ERK) leads to apoptosis inducing factor (AIF) mediated apoptosis in epithelial breast cancer cells: the lack of effect of ERK in p53 mediated copper induced apoptosis. 2005 Aug 15 2
21 15899123 Phosphorylated extracellular signal-regulated kinase up-regulated p53 expression in shikonin-induced HeLa cell apoptosis. 2005 Apr 20 1
22 15116093 Phosphorylation of p53 on Thr55 by ERK2 is necessary for doxorubicin-induced p53 activation and cell death. 2004 Apr 29 2
23 15179185 Deacetylase inhibition in malignant melanomas: impact on cell cycle regulation and survival. 2004 Jun 1
24 15212949 Dual and opposing roles of ERK in regulating G(1) and S-G(2)/M delays in A549 cells caused by hyperoxia. 2004 Jul 15 2
25 14511359 Activation of p53 signalling in acetylsalicylic acid-induced apoptosis in OC2 human oral cancer cells. 2003 Oct 1
26 12065679 Induction of p53 accumulation by Moloney murine leukemia virus-ts1 infection in astrocytes via activation of extracellular signal-regulated kinases 1/2. 2002 Jun 2
27 12439598 Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines. 2002 Nov 1
28 11245472 Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase. 2001 Feb 15 3
29 11314025 p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling. 2001 Feb 22 1
30 10050883 Thrombopoietin-induced conformational change in p53 lies downstream of the p44/p42 mitogen activated protein kinase cascade in the human growth factor-dependent cell line M07e. 1999 Feb 18 3
31 10547071 The expression of p53 tumor suppressor gene in breast cancer cells is down-regulated by cytokine oncostatin M. 1999 Oct 2
32 9588214 IGF I induction of p53 requires activation of MAP kinase in cardiac muscle cells. 1998 Apr 28 1