8 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 30253242 | The development of piperidinones as potent MDM2-P53 protein-protein interaction inhibitors for cancer therapy. | 2018 Nov 5 | 4 |
2 | 24456472 | Discovery of AMG 232, a potent, selective, and orally bioavailable MDM2-p53 inhibitor in clinical development. | 2014 Feb 27 | 1 |
3 | 24548297 | Selective and potent morpholinone inhibitors of the MDM2-p53 protein-protein interaction. | 2014 Mar 27 | 1 |
4 | 24601644 | Novel inhibitors of the MDM2-p53 interaction featuring hydrogen bond acceptors as carboxylic acid isosteres. | 2014 Apr 10 | 1 |
5 | 24967612 | Discovery of a small molecule MDM2 inhibitor (AMG 232) for treating cancer. | 2014 Aug 14 | 1 |
6 | 25042256 | Optimization beyond AMG 232: discovery and SAR of sulfonamides on a piperidinone scaffold as potent inhibitors of the MDM2-p53 protein-protein interaction. | 2014 Aug 15 | 2 |
7 | 25384157 | Discovery of AM-7209, a potent and selective 4-amidobenzoic acid inhibitor of the MDM2-p53 interaction. | 2014 Dec 26 | 1 |
8 | 22991965 | Ordering of the N-terminus of human MDM2 by small molecule inhibitors. | 2012 Oct 17 | 1 |