2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid

tumor protein p53 ; Homo sapiens







13 Article(s)
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1 30367486 Inhibition of the formation of autophagosome but not autolysosome augments ABT-751-induced apoptosis in TP53-deficient Hep-3B cells. 2019 Jun 4
2 28843007 Bcl-2 protects TK6 cells against hydroquinone-induced apoptosis through PARP-1 cytoplasm translocation and stabilizing mitochondrial membrane potential. 2018 Jan 1
3 26704388 Combination of galectin inhibitor GCS-100 and BH3 mimetics eliminates both p53 wild type and p53 null AML cells. 2016 Apr 3
4 26893664 Enhanced anticancer effect of ABT-737 in combination with naringenin on gastric cancer cells. 2016 Feb 1
5 26996126 Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells. 2016 Apr 29 2
6 25548100 Reversal of Mutant KRAS-Mediated Apoptosis Resistance by Concurrent Noxa/Bik Induction and Bcl-2/Bcl-xL Antagonism in Colon Cancer Cells. 2015 Apr 1
7 25181509 Inhibition of the MDM2 E3 Ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with ABT-737. 2014 1
8 22002102 p53-dependent regulation of Mcl-1 contributes to synergistic cell death by ionizing radiation and the Bcl-2/Bcl-XL inhibitor ABT-737. 2012 Feb 3
9 22759956 AMP converted from intracellularly transported adenosine upregulates p53 expression to induce malignant pleural mesothelioma cell apoptosis. 2012 1
10 22875003 Bcl-2 is a better ABT-737 target than Bcl-xL or Bcl-w and only Noxa overcomes resistance mediated by Mcl-1, Bfl-1, or Bcl-B. 2012 Aug 9 2
11 21084274 The BH3 mimetic ABT-737 induces cancer cell senescence. 2011 Jan 15 2
12 21398407 Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737. 2011 May 15 2
13 22101337 Poly(ADP-ribose) polymerase inhibition enhances p53-dependent and -independent DNA damage responses induced by DNA damaging agent. 2011 Dec 1 3