Etoposide

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







18 Article(s)
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1 34243013 Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play. 2021 Oct 2
2 30920135 Regulation of drug metabolizing enzymes in the leukaemic bone marrow microenvironment. 2019 Jun 1
3 30533000 Pharmacokinetic interaction between mitotane and etoposide in adrenal carcinoma: a pilot study. 2018 Dec 1 1
4 25915157 Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes. 2015 Jun 20 1
5 23254912 Effects of morin on the pharmacokinetics of etoposide in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female Sprague-Dawley rats. 2013 Mar 1
6 23981337 Enhanced intestinal absorption of etoposide by self-microemulsifying drug delivery systems: roles of P-glycoprotein and cytochrome P450 3A inhibition. 2013 Nov 20 4
7 22764771 Pharmacologic modulation strategies to reduce dose requirements of anticancer therapy while preserving clinical efficacy. 2012 Jun 1
8 21333639 Involvement of P-glycoprotein and CYP 3A4 in the enhancement of etoposide bioavailability by a piperine analogue. 2011 Apr 25 2
9 21595477 Etoposide quinone is a redox-dependent topoisomerase II poison. 2011 Jun 28 3
10 22687664 Metyrapone: a management option for ectopic ACTH syndrome in small cell lung cancer treated with intravenous etoposide. 2011 Aug 4 2
11 17634410 Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas. 2007 Nov 1 1
12 16753237 Bioconversion of deoxypodophyllotoxin into epipodophyllotoxin in E. coli using human cytochrome P450 3A4. 2006 Nov 10 1
13 17168690 Characterization of an etoposide-glutathione conjugate derived from metabolic activation by human cytochrome p450. 2006 Dec 1
14 12969965 Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia. 2004 Jan 1 1
15 15319341 Kinetics and regulation of cytochrome P450-mediated etoposide metabolism. 2004 Sep 2
16 11473400 Simultaneous determination of etoposide and its catechol metabolite in the plasma of pediatric patients by liquid chromatography/tandem mass spectrometry. 2001 Jul 2
17 9732391 A study on the metabolism of etoposide and possible interactions with antitumor or supporting agents by human liver microsomes. 1998 Sep 1
18 8114683 O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. 1994 Feb 2