Acetylcysteine

nuclear factor kappa B subunit 1 ; Homo sapiens







123 Article(s)
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1 33030807 Molecular mechanisms of quinalizarin induces apoptosis and G0/G1 cell cycle of human esophageal cancer HCE-4 cells depends on MAPK, STAT3, and NF-κB signaling pathways. 2021 Feb 2
2 33712045 Insulin-like growth factor binding protein 3 promotes radiosensitivity of oral squamous cell carcinoma cells via positive feedback on NF-κB/IL-6/ROS signaling. 2021 Mar 13 2
3 34208683 N-Acetylcysteine (NAC): Impacts on Human Health. 2021 Jun 16 2
4 34494136 Diabetes concomitant to aortic stenosis is associated with increased expression of NF-κB and more pronounced valve calcification. 2021 Nov 1
5 34510229 Cadmium induces renal inflammation by activating the NLRP3 inflammasome through ROS/MAPK/NF-κB pathway in vitro and in vivo. 2021 Nov 2
6 34576117 Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells. 2021 Sep 15 1
7 32322478 Efficacy of glutathione therapy in relieving dyspnea associated with COVID-19 pneumonia: A report of 2 cases. 2020 1
8 32361974 Endosulfan induces endothelial inflammation and dysfunction via IRE1α/NF-κB signaling pathway. 2020 Jul 1
9 32534175 Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials. 2020 Oct 1
10 32706497 Simvastatin abolishes nitric oxide- and reactive oxygen species-induced cyclooxygenase-2 expression by blocking the nuclear factor κB pathway in rabbit articular chondrocytes. 2020 Oct 3
11 33149614 Zeaxanthin Induces Apoptosis via ROS-Regulated MAPK and AKT Signaling Pathway in Human Gastric Cancer Cells. 2020 2
12 30394176 Zn-doped CuO nanocomposites inhibit tumor growth by NF-κB pathway cross-linked autophagy and apoptosis. 2019 Jan 1
13 30916421 Glycitein induces reactive oxygen species-dependent apoptosis and G0/G1 cell cycle arrest through the MAPK/STAT3/NF-κB pathway in human gastric cancer cells. 2019 Aug 2
14 31068539 Titanium dioxide nanoparticles induce COX-2 expression through ROS generation in human periodontal ligament cells. 2019 2
15 31545445 N‑acetyl cysteine protects HUVECs against lipopolysaccharide‑mediated inflammatory reaction by blocking the NF‑κB signaling pathway. 2019 Nov 3
16 31577702 N-acetyl cysteine inhibits lipopolysaccharide-mediated synthesis of interleukin-1β and tumor necrosis factor-α in human periodontal ligament fibroblast cells through nuclear factor-kappa B signaling. 2019 Oct 5
17 31934265 Simvastatin Mitigates Apoptosis and Transforming Growth Factor-Beta Upregulation in Stretch-Induced Endothelial Cells. 2019 1
18 29291542 Protocatechuic acid inhibits Toll-like receptor-4-dependent activation of NF-κB by suppressing activation of the Akt, mTOR, JNK and p38-MAPK. 2018 Feb 1
19 30037745 Microwave ablation combined with doxorubicin enhances cell death via promoting reactive oxygen species generation in breast cancer cells. 2018 Dec 2
20 30415238 Effect of thiol antioxidants on lipopolysaccharide-induced cyclooxygenase-2 expression in pulmonary epithelial cells. 2018 Aug 2
21 28063998 Inhibiting ROS-NF-κB-dependent autophagy enhanced brazilin-induced apoptosis in head and neck squamous cell carcinoma. 2017 Mar 2
22 28271166 N-Acetylcysteine improves intestinal function in lipopolysaccharides-challenged piglets through multiple signaling pathways. 2017 Dec 1
23 28341536 The role of cPLA2 in Methylglyoxal-induced cell apoptosis of HUVECs. 2017 May 15 2
24 28432555 Rotundarpene inhibits TNF-α-induced activation of the Akt, mTOR, and NF-κB pathways, and the JNK and p38 associated with production of reactive oxygen species. 2017 Oct 1
25 28482716 Dihydromyricetin induces apoptosis and cytoprotective autophagy through ROS-NF-κB signalling in human melanoma cells. 2017 May 2
26 28705740 Proteomics analysis of human placenta reveals glutathione metabolism dysfunction as the underlying pathogenesis for preeclampsia. 2017 Sep 1
27 25876056 PM2.5-induced oxidative stress increases adhesion molecules expression in human endothelial cells through the ERK/AKT/NF-κB-dependent pathway. 2016 Jan 2
28 26683377 Dimethyl Fumarate Inhibits the Nuclear Factor κB Pathway in Breast Cancer Cells by Covalent Modification of p65 Protein. 2016 Feb 12 1
29 27005845 Soyasaponin Bb inhibits the recruitment of toll-like receptor 4 (TLR4) into lipid rafts and its signaling pathway by suppressing the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-dependent generation of reactive oxygen species. 2016 Jul 1
30 27084536 Thymoquinone inhibits growth of human medulloblastoma cells by inducing oxidative stress and caspase-dependent apoptosis while suppressing NF-κB signaling and IL-8 expression. 2016 May 1
31 27221774 Flavonoid myricetin inhibits TNF-α-stimulated production of inflammatory mediators by suppressing the Akt, mTOR and NF-κB pathways in human keratinocytes. 2016 Aug 5 1
32 27475664 Advanced oxidation protein products induce catabolic effect through oxidant-dependent activation of NF-κ B pathway in human chondrocyte. 2016 Oct 1
33 27572503 Curcumin inhibits H2O2-induced invasion and migration of human pancreatic cancer via suppression of the ERK/NF-κB pathway. 2016 Oct 1
34 27932980 TNF-α-Induced cPLA2 Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-κB Cascade on Human Pulmonary Alveolar Epithelial Cells. 2016 3
35 25503516 Regulation of Cigarette Smoke Induction of IL-8 in Macrophages by AMP-activated Protein Kinase Signaling. 2015 Aug 1
36 25732260 Involvement of NFκB signaling in mediating the effects of GRK5 on neural stem cells. 2015 May 22 2
37 25862169 Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling. 2015 May 3
38 25971793 Sesquiterpene lactone parthenolide attenuates production of inflammatory mediators by suppressing the Toll-like receptor-4-mediated activation of the Akt, mTOR, and NF-κB pathways. 2015 Sep 1
39 25972196 The role of NF-κB in PARP-inhibitor-mediated sensitization and detoxification of arsenic trioxide in hepatocellular carcinoma cells. 2015 Jun 1
40 26118633 Saikosaponin-D reduces cisplatin-induced nephrotoxicity by repressing ROS-mediated activation of MAPK and NF-κB signalling pathways. 2015 Sep 2
41 26184135 Nitric Oxide-Releasing Aspirin Suppresses NF-κB Signaling in Estrogen Receptor Negative Breast Cancer Cells in Vitro and in Vivo. 2015 Jul 9 1
42 24552822 Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways. 2014 2
43 24609059 Mitochondrial dysfunction promotes and aggravates the inflammatory response in normal human synoviocytes. 2014 Jul 1
44 25257100 N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NFκB pathway. 2014 Sep 7
45 25350954 Thymidine phosphorylase activates NFκB and stimulates the expression of angiogenic and metastatic factors in human cancer cells. 2014 Nov 15 1
46 23065916 N-Acetylcysteine in hemodialysis diabetic patients resets the activation of NF-kB in lymphomonocytes to normal values. 2013 Jul-Aug 3
47 23407882 CREB, NF-κB, and NADPH oxidase coordinately upregulate indoxyl sulfate-induced angiotensinogen expression in proximal tubular cells. 2013 Apr 1 1
48 22134636 Pro-oxidant and antioxidant effects of N-acetylcysteine regulate doxorubicin-induced NF-kappa B activity in leukemic cells. 2012 Feb 8
49 22825625 PI3Kγ activation is required for LPS-induced reactive oxygen species generation in respiratory epithelial cells. 2012 Nov 1
50 20625996 Reactive oxygen species are involved in the IFN-γ-stimulated production of Th2 chemokines in HaCaT keratinocytes. 2011 Jan 3