Oligonucleotides

telomerase reverse transcriptase ; Homo sapiens







50 Article(s)
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Pub. Year
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1 34710826 Antisense oligonucleotide repress telomerase activity via manipulating alternative splicing or translation. 2021 Dec 10 2
2 32825005 Oligonucleotides and microRNAs Targeting Telomerase Subunits in Cancer Therapy. 2020 Aug 19 1
3 30612734 Inhibition of telomerase activity by splice-switching oligonucleotides targeting the mRNA of the telomerase catalytic subunit affects proliferation of human CD4+ T lymphocytes. 2019 Feb 12 1
4 30887243 A novel antisense oligonucleotide anchored on the intronic splicing enhancer of hTERT pre-mRNA inhibits telomerase activity and induces apoptosis in glioma cells. 2019 May 1
5 30892312 Visualizing the down-regulation of hTERT mRNA expression using gold-nanoflare probes and verifying the correlation with cancer cell apoptosis. 2019 May 7 2
6 29563163 Anti-hTERT siRNA-Loaded Nanoparticles Block the Growth of Anaplastic Thyroid Cancer Xenograft. 2018 Jun 1
7 28291810 MicroRNA-532 and microRNA-3064 inhibit cell proliferation and invasion by acting as direct regulators of human telomerase reverse transcriptase in ovarian cancer. 2017 1
8 28425985 The cellular senescence of leukemia-initiating cells from acute lymphoblastic leukemia is postponed by β-Arrestin1 binding with P300-Sp1 to regulate hTERT transcription. 2017 Apr 20 1
9 28627628 Phosphorothioate‑modified antisense oligonucleotides against human telomerase reverse transcriptase sensitize cancer cells to radiotherapy. 2017 Aug 3
10 29657298 A Novel Long Non-Coding RNA in the hTERT Promoter Region Regulates hTERT Expression. 2017 Dec 29 1
11 26742579 Inhibition of human telomerase reverse transcriptase in vivo and in vitro for retroviral vector-based antisense oligonucleotide therapy in ovarian cancer. 2016 Jan 2
12 27797329 [Apoptotic endonuclease EndoG regulates alternative splicing of human telomerase catalytic subunit hTERT]. 2016 Jul 2
13 25666290 Can Carrier-Mediated Delivery System Promote the Development of Antisense Imaging? 2015 Oct 1
14 26332545 A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis. 2015 Sep 3 1
15 24307558 Molecular imaging and pharmacokinetics of (99m) Tc-hTERT antisense oligonucleotide as a potential tumor imaging probe. 2014 Feb 3
16 24610620 Bioinformatics analysis of Exonic Splicing Enhancers (ESEs) for predicting potential regulatory elements of hTERT mRNA splicing. 2014 2
17 25187833 Antisense oligodeoxynucleotide against human telomerase reverse transcriptase inhibits the proliferation of Eca-109 esophageal carcinoma cells. 2014 Oct 1
18 23562158 Regulation of telomerase alternative splicing: a target for chemotherapy. 2013 Apr 25 1
19 22848504 Antisense oligonucleotide against hTERT (Cantide) inhibits tumor growth in an orthotopic primary hepatic lymphoma mouse model. 2012 1
20 22893708 Specificity requirements for human telomere protein interaction with telomerase holoenzyme. 2012 Oct 5 1
21 20347571 Administration with telomeric DNA telomere-like oligonucleotides induces enhancement of telomerase activity and resistance against oxidative stress in telomere reverse transcriptase gene-transfected human fibroblasts. 2010 Oct 1
22 18837440 Telomerase-targeting antisense oligonucleotides carried by polycation liposomes enhance the growth inhibition effect on tumor cells. 2009 May 1
23 19623161 Coadministration of telomerase genetic vaccine and a novel TLR9 agonist in nonhuman primates. 2009 Oct 1
24 20137691 [Effect of human telomerase reverse transcriptase gene antisense oligonucleotide on sensitivity of gemcitabine in pancreatic cancer cell]. 2009 Sep 15 2
25 21475859 Antitumor efficacy of human telomerase reverse transcriptase gene antisense oligonucleotide in pancreatic cancer cells. 2009 May-Jun 2
26 18836295 An investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells. 2008 Nov 1
27 17438368 The inhibitory effects of nanosize delivery system for antisense oligonucleotide of hTERT on EC9706 cells. 2007 Mar 2
28 17560709 A model for triple helix formation on human telomerase reverse transcriptase (hTERT) promoter and stabilization by specific interactions with the water soluble perylene derivative, DAPER. 2007 Aug 2
29 18006621 Noninvasive imaging of human telomerase reverse transcriptase (hTERT) messenger RNA with 99mTc-radiolabeled antisense probes in malignant tumors. 2007 Dec 3
30 16615118 Microarray analyses in bladder cancer cells: inhibition of hTERT expression down-regulates EGFR. 2006 Sep 15 2
31 17177836 Telomerase antisense inhibition for the proliferation of endometrial cancer in vitro and in vivo. 2006 Nov-Dec 1
32 15682468 Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell line. 2005 Feb 14 1
33 15737568 Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells. 2005 Mar 2
34 15829059 Targeted therapy of human laryngeal squamous cell carcinoma in vitro by antisense oligonucleotides directed against telomerase reverse transcriptase mRNA. 2005 Feb 3
35 15832424 Combined effects of Cantide and chemotherapeutic drugs on inhibition of tumor cells' growth in vitro and in vivo. 2005 Apr 28 1
36 15862164 [The effect of short hairpin RNA on hTERT expression]. 2005 May 1
37 15890091 [Inhibiting expression of human telomerase reverse transcriptase promotes degradation of survivin protein]. 2005 May 2
38 15902727 Effect of vector-expressed shRNAs on hTERT expression. 2005 May 21 1
39 15916744 Inhibition of tumor growth and metastasis with antisense oligonucleotides (Cantide) targeting hTERT in an in situ human hepatocellular carcinoma model. 2005 Jun 1
40 14717587 Inhibition of telomerase activity by preventing proper assemblage. 2004 Jan 20 1
41 14760759 Antisense oligonucleotide targeting at the initiator of hTERT arrests growth of hepatoma cells. 2004 Feb 1 1
42 15199161 Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT). 2004 Jul 2
43 15257899 [Detection of human telomerase reverse transcriptase mRNA of cells in pleural fluid by two-step in situ hybridization using digoxin-labeled oligonucleotide probes]. 2004 Jul 1
44 15569435 [Telomerase antisense inhibition and chemotherapeutic combination treatments for the proliferation of endometrial cancer in vitro and in vivo]. 2004 Oct 17 1
45 15665594 Telomerase reverse transcriptase (hTERT) mRNA and telomerase RNA (hTR) as targets for downregulation of telomerase activity. 2004 Winter 1
46 20641541 [99mTc]Human telomerase reverse-transcriptase antisense mRNA oligonucleotide 2004 1
47 12519411 Demonstration of human telomerase reverse transcriptase (hTERT) in human parathyroid tumours by in situ hybridization with a new oligonucleotide probe. 2003 Jan 2
48 12838868 [Targeted therapy of human laryngeal squamous cell carcinoma in vitro with telomerase catalytic subunit mRNA]. 2003 Apr 1
49 14563552 Induction of endogenous telomerase (hTERT) by c-Myc in WI-38 fibroblasts transformed with specific genetic elements. 2003 Oct 16 1
50 12678728 How to inhibit telomerase activity for cancer therapy. 2002 Sep 1