| 1 |
35549943 | Sustained correction of hippocampal neurogenic and cognitive deficits after a brief treatment by Nutlin-3 in a mouse model of fragile X syndrome. | 2022 May 13 |
2 |
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34601706 | Targeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degeneration. | 2021 Dec |
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| 3 |
31004033 | Non-genotoxic MDM2 inhibition selectively induces a pro-apoptotic p53 gene signature in chronic lymphocytic leukemia cells. | 2019 Dec |
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| 4 |
31083332 | MDM2-Mediated p21 Proteasomal Degradation Promotes Fluoride Toxicity in Ameloblasts. | 2019 May 10 |
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| 5 |
31472117 | Iduna protects HT22 cells by inhibiting parthanatos: The role of the p53-MDM2 pathway. | 2019 Nov 1 |
1 |
| 6 |
30126549 | Inhibition of Noncanonical Murine Double Minute 2 Homolog Abrogates Ocular Inflammation through NF-κB Suppression. | 2018 Sep |
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| 7 |
26578686 | Phosphorylation of murine double minute-2 on Ser166 is downstream of VEGF-A in exercised skeletal muscle and regulates primary endothelial cell migration and FoxO gene expression. | 2016 Mar |
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| 8 |
24777400 | [Localization and expression pattern of MDM2 in axon initial segments of neuron in rodent brain]. | 2014 Apr 25 |
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| 9 |
21557332 | Pharmacological inhibition of Mdm2 triggers growth arrest and promotes DNA breakage in mouse colon tumors and human colon cancer cells. | 2012 May |
1 |
| 10 |
22465010 | Reversible induction of PARP1 degradation by p53-inducible cis-imidazoline compounds. | 2012 Apr 27 |
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| 11 |
21205074 | Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells. | 2011 Mar |
2 |
| 12 |
21498419 | Inhibition of MDM2 attenuates neointimal hyperplasia via suppression of vascular proliferation and inflammation. | 2011 Sep 1 |
1 |
| 13 |
21498692 | HMGA2 and p14Arf: major roles in cellular senescence of fibroids and therapeutic implications. | 2011 Mar |
1 |
| 14 |
21949095 | Mdm2 promotes systemic lupus erythematosus and lupus nephritis. | 2011 Nov |
1 |
| 15 |
20588277 | Nutlin-3, the small-molecule inhibitor of MDM2, promotes senescence and radiosensitises laryngeal carcinoma cells harbouring wild-type p53. | 2010 Jul 13 |
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| 16 |
20849464 | p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation. | 2010 Dec |
1 |
| 17 |
19385969 | Cyclin-dependent kinase 1 inhibitor RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis in AML. | 2009 Jun |
1 |
| 18 |
19903807 | Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53. | 2009 Nov 18 |
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| 19 |
18273046 | MDM2 antagonist nutlin-3 is a potent inducer of apoptosis in pediatric acute lymphoblastic leukemia cells with wild-type p53 and overexpression of MDM2. | 2008 Apr |
2 |
| 20 |
18567799 | Mdm2 and Mdm4 loss regulates distinct p53 activities. | 2008 Jun |
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| 21 |
17364023 | Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas. | 2007 Apr |
3 |
| 22 |
17709487 | Respiratory syncytial virus decreases p53 protein to prolong survival of airway epithelial cells. | 2007 Sep 1 |
1 |
| 23 |
16949053 | Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors. | 2006 Oct 16 |
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