Fatty Acids

peroxisome proliferator activated receptor alpha ; Mus musculus







441 Article(s)
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1 35046382 STAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation. 2022 Jan 19 1
2 35149852 Hepatic NCoR1 deletion exacerbates alcohol-induced liver injury in mice by promoting CCL2-mediated monocyte-derived macrophage infiltration. 2022 Feb 11 1
3 35150895 Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis. 2022 Apr 1
4 35183812 Chronic exposure to low-dose cadmium facilitated nonalcoholic steatohepatitis in mice by suppressing fatty acid desaturation. 2022 Mar 15 1
5 35203398 Basal Autophagy Is Necessary for A Pharmacologic PPARα Transactivation. 2022 Feb 21 2
6 35224041 Downregulation of PTEN Promotes Autophagy via Concurrent Reduction in Apoptosis in Cardiac Hypertrophy in PPAR α-/- Mice. 2022 2
7 35419389 Hepatic PPARα Is Destabilized by SIRT1 Deacetylase in Undernourished Male Mice. 2022 2
8 35428314 L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway. 2022 Apr 15 2
9 35460276 Intestinal peroxisome proliferator-activated receptor α-fatty acid-binding protein 1 axis modulates nonalcoholic steatohepatitis. 2022 Apr 23 5
10 35526488 PPARα agonist WY-14,643 induces the PLA2/COX-2/ACOX1 pathway to enhance peroxisomal lipid metabolism and ameliorate alcoholic fatty liver in mice. 2022 Jul 12 2
11 35533983 Transcriptional Integration of Distinct Microbial and Nutritional Signals by the Small Intestinal Epithelium. 2022 May 6 1
12 35538760 [Mechanism of Triclosan in the Treatment of Nonalcoholic Fatty Liver Disease Based on Network Pharmacology]. 2022 Apr 1
13 33093014 ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway. 2021 Jan 1
14 33184849 Co-option of PPARα in the regulation of lipogenesis and fatty acid oxidation in CLA-induced hepatic steatosis. 2021 Jun 1
15 33257471 Hepatic Krüppel-like factor 16 (KLF16) targets PPARα to improve steatohepatitis and insulin resistance. 2021 Nov 2
16 33352397 IL-8 exacerbates alcohol-induced fatty liver disease via the Akt/HIF-1α pathway in human IL-8-expressing mice. 2021 Feb 2
17 33417961 Icaritin ameliorates hepatic steatosis via promoting fatty acid β-oxidation and insulin sensitivity. 2021 Mar 1 1
18 33491665 Discordant hepatic fatty acid oxidation and triglyceride hydrolysis leads to liver disease. 2021 Jan 25 1
19 33500723 Activation of N-methyl-D-aspartate receptor regulates insulin sensitivity and lipid metabolism. 2021 1
20 33758172 Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver. 2021 Mar 23 4
21 33785868 Ahnak deficiency attenuates high-fat diet-induced fatty liver in mice through FGF21 induction. 2021 Mar 1
22 33798787 Hypoxia via ERK Signaling Inhibits Hepatic PPARα to Promote Fatty Liver. 2021 2
23 33892114 PPARα agonist WY-14,643 enhances ethanol metabolism in mice: Role of catalase. 2021 Jun 2
24 33916086 Fenofibrate Regulates Visceral Obesity and Nonalcoholic Steatohepatitis in Obese Female Ovariectomized C57BL/6J Mice. 2021 Apr 1 1
25 33934381 Hepatic Small Ubiquitin-Related Modifier (SUMO)-Specific Protease 2 Controls Systemic Metabolism Through SUMOylation-Dependent Regulation of Liver-Adipose Tissue Crosstalk. 2021 Oct 2
26 34052195 Fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, blocks steatosis and alters the inflammatory response in a mouse model of inflammation-dioxin interaction. 2021 Aug 25 2
27 34092291 Silybin alleviates hepatic lipid accumulation in methionine-choline deficient diet-induced nonalcoholic fatty liver disease in mice via peroxisome proliferator-activated receptor α. 2021 Jun 1
28 34116071 Liver-specific Nrf2 deficiency accelerates ethanol-induced lethality and hepatic injury in vivo. 2021 Sep 1 1
29 34192547 FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes. 2021 Jun 29 1
30 34207854 Pemafibrate Protects against Fatty Acid-Induced Nephropathy by Maintaining Renal Fatty Acid Metabolism. 2021 Jun 9 1
31 34244236 PPARα Agonist Fenofibrate Enhances Cancer Vaccine Efficacy. 2021 Sep 1 1
32 34267188 Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway. 2021 Jul 15 2
33 34268878 Pectic Oligogalacturonide Facilitates the Synthesis and Activation of Adiponectin to Improve Hepatic Lipid Oxidation. 2021 Oct 1
34 34281337 γ-Linolenic Acid Prevents Lipid Metabolism Disorder in Palmitic Acid-Treated Alpha Mouse Liver-12 Cells by Balancing Autophagy and Apoptosis via the LKB1-AMPK-mTOR Pathway. 2021 Jul 28 1
35 34288722 Hepatic ADTRP overexpression does not influence lipid and glucose metabolism. 2021 Oct 1 1
36 34347073 3' untranslated region of Ckip-1 inhibits cardiac hypertrophy independently of its cognate protein. 2021 Sep 21 1
37 34380027 GDF15 mediates the metabolic effects of PPARβ/δ by activating AMPK. 2021 Aug 10 1
38 34380288 Comprehensive multi-omics approaches reveal the hepatotoxic mechanism of perfluorohexanoic acid (PFHxA) in mice. 2021 Oct 10 2
39 34415766 Novel ι-Carrageenan Tetrasaccharide Alleviates Liver Lipid Accumulation via the Bile Acid-FXR-SHP/PXR Pathway to Regulate Cholesterol Conversion and Fatty Acid Metabolism in Insulin-Resistant Mice. 2021 Sep 1 4
40 34422410 ANGPTL4 Attenuates Ang II-Induced Atrial Fibrillation and Fibrosis in Mice via PPAR Pathway. 2021 1
41 34454927 β-elemene blocks lipid-induced inflammatory pathways via PPARβ activation in heart failure. 2021 Nov 5 1
42 34474167 PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during fasting by modulating protein stability of PPARα. 2021 Nov 1
43 34615341 Critical role of peroxisome proliferator-activated receptor α in promoting platelet hyperreactivity and thrombosis under hyperlipidemia. 2021 Oct 7 1
44 34986301 The Effects of PPAR Agonists on Atherosclerosis and Nonalcoholic Fatty Liver Disease in ApoE-/-FXR-/- Mice. 2021 Dec 1
45 35087411 Aurantio-Obtusin Attenuates Non-Alcoholic Fatty Liver Disease Through AMPK-Mediated Autophagy and Fatty Acid Oxidation Pathways. 2021 1
46 31785270 Sleep profile during fasting in PPAR-alpha knockout mice. 2020 Feb 1 1
47 31914699 Palmitoylethanolamide counteracts hepatic metabolic inflexibility modulating mitochondrial function and efficiency in diet-induced obese mice. 2020 Jan 1
48 32070771 Effects of clofibrate and KH176 on life span and motor function in mitochondrial complex I-deficient mice. 2020 Jun 1 2
49 32145476 Ambient fine particulate matter disrupts hepatic circadian oscillation and lipid metabolism in a mouse model. 2020 Jul 2
50 32192216 PPARs as Metabolic Regulators in the Liver: Lessons from Liver-Specific PPAR-Null Mice. 2020 Mar 17 1