benzyloxycarbonylleucyl-leucyl-leucine aldehyde

caspase 3 ; Homo sapiens







52 Article(s)
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1 33482188 The inhibitive effects of proteasome inhibitor MG-132 on pterygium fibroblasts in vitro and the potential key regulators involved. 2021 Apr 1 1
2 34002651 Proteasome inhibitor MG132 induces apoptosis in human osteosarcoma U2OS cells. 2021 Nov 1
3 32184020 Involvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+leukemia cells. 2020 May 14 1
4 30488656 The homozygous variant c.797G>A/p.(Cys266Tyr) in PISD is associated with a Spondyloepimetaphyseal dysplasia with large epiphyses and disturbed mitochondrial function. 2019 Mar 1
5 31687087 Pueraria lobata and Daidzein Reduce Cytotoxicity by Enhancing Ubiquitin-Proteasome System Function in SCA3-iPSC-Derived Neurons. 2019 2
6 30091530 ING5-mediated antineuroblastoma effects of suberoylanilide hydroxamic acid. 2018 Sep 1
7 30442180 Modeling hallmark pathology using motor neurons derived from the family and sporadic amyotrophic lateral sclerosis patient-specific iPS cells. 2018 Nov 15 1
8 26648402 Induction of autophagy by the MG‑132 proteasome inhibitor is associated with endoplasmic reticulum stress in MCF‑7 cells. 2016 Jan 1
9 27051056 Proteasome Inhibitor MG132 Enhances Sensitivity to Cisplatin on Ovarian Carcinoma Cells In Vitro and In Vivo. 2016 Jun 1
10 27091487 Carnosic acid protects SH-SY5Y cells against 6-hydroxydopamine-induced cell death through upregulation of parkin pathway. 2016 Nov 1
11 27277541 Proteasome inhibitor MG132 potentiates TRAIL-induced apoptosis in gallbladder carcinoma GBC-SD cells via DR5-dependent pathway. 2016 Aug 1
12 27774335 N-Acetylcysteine in Combination with IGF-1 Enhances Neuroprotection against Proteasome Dysfunction-Induced Neurotoxicity in SH-SY5Y Cells. 2016 1
13 26137056 Inhibition of autophagy promotes cell apoptosis induced by the proteasome inhibitor MG-132 in human esophageal squamous cell carcinoma EC9706 cells. 2015 May 1
14 26165741 Dissociation of E-cadherin/β-catenin complex by MG132 and bortezomib enhances CDDP induced cell death in oral cancer SCC-25 cells. 2015 Dec 1
15 24584782 Proteasome inhibitor MG132 inhibits the proliferation and promotes the cisplatin-induced apoptosis of human esophageal squamous cell carcinoma cells. 2014 May 1
16 23445492 Pentoxifylline and the proteasome inhibitor MG132 induce apoptosis in human leukemia U937 cells through a decrease in the expression of Bcl-2 and Bcl-XL and phosphorylation of p65. 2013 Feb 28 1
17 23994633 Proteasome inhibitor MG132 enhances TRAIL-induced apoptosis and inhibits invasion of human osteosarcoma OS732 cells. 2013 Sep 20 1
18 22310719 Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β. 2012 Feb 24 1
19 22388098 Pseudolaric acid B induces apoptosis via proteasome-mediated Bcl-2 degradation in hormone-refractory prostate cancer DU145 cells. 2012 Jun 1
20 22538490 Modeling Parkinson's disease using induced pluripotent stem cells. 2012 Jun 1
21 22791147 Ursolic acid from Oldenlandia diffusa induces apoptosis via activation of caspases and phosphorylation of glycogen synthase kinase 3 beta in SK-OV-3 ovarian cancer cells. 2012 2
22 22791333 Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress. 2012 Sep 15 1
23 23152053 Proteasome inhibition upregulates Bim and induces caspase-3-dependent apoptosis in human mast cells expressing the Kit D816V mutation. 2012 Nov 15 1
24 21206980 Proteasome inhibitor sensitizes oral squamous cell carcinoma cells to TRAIL-mediated apoptosis. 2011 Mar 1
25 21297867 Proteasome inhibition represses unfolded protein response and Nox4, sensitizing vascular cells to endoplasmic reticulum stress-induced death. 2011 Jan 26 1
26 19646807 The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation. 2010 Feb 28 1
27 20005289 Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition. 2010 Apr 1
28 20305374 Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells. 2010 Apr 1 1
29 20651358 Attenuation of MG132-induced HeLa cell death by N-acetyl cysteine via reducing reactive oxygen species and preventing glutathione depletion. 2010 Jun 1
30 19229559 SCA8 repeat expansion: large CTA/CTG repeat alleles in neurological disorders and functional implications. 2009 May 1
31 19374806 [Induction of apoptosis by proteasome inhibitor MG-132 in human erythroleukemia cell line K562]. 2009 Apr 2
32 18064564 Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells. 2008 Nov 1
33 18298651 Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation. 2008 Dec 4
34 18492488 Proteasome inhibitors induce osteoclast survival by activating the Akt pathway. 2008 Dec 5 1
35 16287099 Proteasome inhibitor MG132 sensitizes HPV-positive human cervical cancer cells to rhTRAIL-induced apoptosis. 2006 Apr 15 1
36 16337881 Oxidative stress response results in increased p21WAF1/CIP1 degradation in cystic fibrosis lung epithelial cells. 2006 Jan 1 1
37 16998592 Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria. 2006 1
38 15941855 Polyamine depletion reduces TNFalpha/MG132-induced apoptosis in bone marrow stromal cells. 2005 Aug 1
39 15276073 Differential response of MG132 cytotoxicity against small cell lung cancer cells to changes in cellular GSH contents. 2004 Aug 15 1
40 15289872 Inhibition of the ubiquitin-proteasome pathway activates stress kinases and induces apoptosis in renal cancer cells. 2004 Sep 1
41 15492836 Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis. 2004 Nov 1
42 14513055 The proteasome inhibitor bortezomib promotes mitochondrial injury and apoptosis induced by the small molecule Bcl-2 inhibitor HA14-1 in multiple myeloma cells. 2003 Oct 1
43 12239627 Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-XS and activation of caspase-3. 2002 Oct 2
44 11319608 Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors. 2001 Mar 1
45 11465715 Regulation of CD95 (Fas/APO-1)-induced apoptosis in human chondrocytes. 2001 Jul 1
46 11477551 Inhibition of proteasome function induced apoptosis in gastric cancer. 2001 Aug 15 1
47 11490372 Nuclear factor-kappa B is upregulated in colorectal cancer. 2001 Aug 1
48 12578613 [Induction of Apoptosis in Leukemic Cells by Inhibiting the Ubiquitin-Proteasome Pathway and Its Possible Mechanism] 2001 Jun 2
49 10930537 Prevention of etoposide-induced apoptosis by proteasome inhibitors in a human leukemic cell line but not in fresh acute leukemia blasts. A differential role of NF-kappab activation. 2000 Sep 15 1
50 10229667 Inhibition of ubiquitin-proteasome pathway activates a caspase-3-like protease and induces Bcl-2 cleavage in human M-07e leukaemic cells. 1999 May 15 1