| 1 |
33047658 | Cysteine focused covalent inhibitors against the main protease of SARS-CoV-2. | 2022 Mar |
1 |
| 2 |
34242492 | MPI8 is Potent against SARS-CoV-2 by Inhibiting Dually and Selectively the SARS-CoV-2 Main Protease and the Host Cathepsin L. | 2022 Jan 5 |
2 |
| 3 |
35549342 | Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine. | 2022 Jun 9 |
1 |
| 4 |
32662333 | Computational discovery of small drug-like compounds as potential inhibitors of SARS-CoV-2 main protease. | 2021 Sep |
2 |
| 5 |
33278462 | 2-Pyridone natural products as inhibitors of SARS-CoV-2 main protease. | 2021 Feb 1 |
1 |
| 6 |
33503819 | Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188. | 2021 Jan 25 |
1 |
| 7 |
33570381 | Challenges for Targeting SARS-CoV-2 Proteases as a Therapeutic Strategy for COVID-19. | 2021 Jun 11 |
1 |
| 8 |
33677227 | Docking-based virtual screening studies aiming at the covalent inhibition of SARS-CoV-2 MPro by targeting the cysteine 145. | 2021 Jun |
1 |
| 9 |
34031399 | Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives. | 2021 May 24 |
1 |
| 10 |
34399606 | Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300. | 2021 Aug 31 |
3 |
| 11 |
34418570 | Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors. | 2021 Oct 15 |
1 |
| 12 |
34506130 | Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode. | 2021 Oct 5 |
1 |
| 13 |
34860011 | Discovery of Di- and Trihaloacetamides as Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity. | 2021 Dec 15 |
1 |
| 14 |
35068913 | Supercomputer simulation of the covalent inhibition of the main protease of SARS-CoV-2. | 2021 |
1 |
| 15 |
32321856 | Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease. | 2020 Jun 19 |
1 |
| 16 |
32611087 | Topological analysis of SARS CoV-2 main protease. | 2020 Jun |
1 |
| 17 |
32812956 | Dynamical properties of enzyme-substrate complexes disclose substrate specificity of the SARS-CoV-2 main protease as characterized by the electron density descriptors. | 2020 Sep 8 |
1 |
| 18 |
33063790 | Room-temperature X-ray crystallography reveals the oxidation and reactivity of cysteine residues in SARS-CoV-2 3CL Mpro: insights into enzyme mechanism and drug design. | 2020 Sep 21 |
1 |
| 19 |
33320670 | Proton-Coupled Conformational Activation of SARS Coronavirus Main Proteases and Opportunity for Designing Small-Molecule Broad-Spectrum Targeted Covalent Inhibitors. | 2020 Dec 30 |
1 |