oridonin

BCL2 apoptosis regulator ; Homo sapiens







41 Article(s)
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1 34926196 Combination of oridonin and TRAIL induces apoptosis in uveal melanoma cells by upregulating DR5. 2021 1
2 30229997 Oridonin-induced mitochondria-dependent apoptosis in esophageal cancer cells by inhibiting PI3K/AKT/mTOR and Ras/Raf pathways. 2019 Mar 1
3 30320906 Synergistic antitumor activity of oridonin and valproic acid on HL-60 leukemia cells. 2019 Apr 1
4 29323103 Oridonin exerts anticancer effect on osteosarcoma by activating PPAR-γ and inhibiting Nrf2 pathway. 2018 Jan 11 1
5 29432993 Oridonin inhibits oral cancer growth and PI3K/Akt signaling pathway. 2018 Apr 1
6 30127932 Oridonin inhibits growth and induces apoptosis of human neurocytoma cells via the Wnt/β-catenin pathway. 2018 Sep 2
7 30546402 Oridonin enhances the radiosensitivity of lung cancer cells by upregulating Bax and downregulating Bcl-2. 2018 Dec 2
8 28454475 Oridonin induces G2/M cell cycle arrest and apoptosis via the PI3K/Akt signaling pathway in hormone-independent prostate cancer cells. 2017 Apr 1
9 28822194 [Effect of oridonin on apoptosis and intracellular reactive oxygen species level in triple-negative breast cancer MDA-MB-231 cells]. 2017 Jun 2
10 29256858 Oridonin Induces Apoptosis in Human Nasopharyngeal Carcinoma Cells Involving ROS Generation. 2017 3
11 29290992 Oridonin synergistically enhances JQ1-triggered apoptosis in hepatocellular cancer cells through mitochondrial pathway. 2017 Dec 5 1
12 26676928 A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells. 2016 Feb 1
13 27082253 Oridonin induces apoptosis through the mitochondrial pathway in human gastric cancer SGC-7901 cells. 2016 Jun 2
14 27400478 Inhibitory effect of oridonin on proliferation of RPMI8226 cells and the possible underlying mechanism. 2016 Apr 1
15 25545058 Oridonin induces apoptosis in uveal melanoma cells by upregulation of Bim and downregulation of Fatty Acid Synthase. 2015 Feb 6 1
16 26054686 Oridonin triggers apoptosis in colorectal carcinoma cells and suppression of microRNA-32 expression augments oridonin-mediated apoptotic effects. 2015 May 1
17 24627081 Proteomic and functional analyses demonstrate the involvement of oxidative stress in the anticancer activities of oridonin in HepG2 cells. 2014 May 1
18 24655726 Oridonin induces apoptosis and cell cycle arrest of gallbladder cancer cells via the mitochondrial pathway. 2014 Mar 21 1
19 24763006 [Mechanism concerning antitumor effect of oridonin on multiple myeloma cell line U266]. 2014 Apr 1
20 25242370 Enhancement of the effects of gemcitabine against pancreatic cancer by oridonin via the mitochondrial caspase-dependent signaling pathway. 2014 Dec 6
21 25571712 [Anti-leukemia effect of oridonin on T-cell acute lymphoblastic leukemia]. 2014 Nov 1
22 23336515 Oridonin induces apoptosis, inhibits migration and invasion on highly-metastatic human breast cancer cells. 2013 1
23 24179549 Oridonin induces the apoptosis of metastatic hepatocellular carcinoma cells via a mitochondrial pathway. 2013 Nov 1
24 22791165 Interruption of hepatocyte growth factor signaling augmented oridonin-induced death in human non-small cell lung cancer A549 cells via c-met-nuclear factor-κB-cyclooxygenase-2 and c-Met-Bcl-2-caspase-3 pathways. 2012 3
25 22895079 Oridonin in combination with imatinib exerts synergetic anti-leukemia effect in Ph+ acute lymphoblastic leukemia cells in vitro by inhibiting activation of LYN/mTOR signaling pathway. 2012 Nov 1
26 22967375 [Anti-leukemia effect of oridonin on Ph(+) acute lymphoblastic leukemia cell SUP-B15]. 2012 Jun 2
27 23326121 Oridonin induces apoptosis in gastric cancer through Apaf-1, cytochrome c and caspase-3 signaling pathway. 2012 Dec 28 1
28 21892202 Reactive oxygen species contribute to oridonin-induced apoptosis and autophagy in human cervical carcinoma HeLa cells. 2011 Oct 2
29 21937802 Oridonin induced the apoptosis of PC-3 cells and its mechanism. 2011 Aug 1
30 19921575 [Empirical study of oridonin-induced gastric cancer cells MKN45 apoptosis]. 2009 Nov 1
31 18058384 Oridonin induces human epidermoid carcinoma A431 cell apoptosis through tyrosine kinase and mitochondrial pathway. 2008 Jan-Feb 1
32 17520804 [Mechanism of downregulation of apoptosis by autophagy induced by oridonin in HeLa cells]. 2007 Jan 1
33 17895587 Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells. 2007 Sep 2
34 16432862 Antiproliferation effects of oridonin on HPB-ALL cells and its mechanisms of action. 2006 Feb 1
35 16638644 Oridonin inhibits cell growth by induction of apoptosis on human hepatocelluar carcinoma BEL-7402 cells. 2006 Jun 2
36 17260801 [Change of Bcl-2 expression and telomerase during apoptosis induced by oridonin on human hepatocelluar carcinoma cells]. 2006 Nov 4
37 15703811 The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage. 2005 Mar 2
38 15827331 Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways. 2005 Apr 2
39 16019488 Apoptotic effect of oridonin on NB4 cells and its mechanism. 2005 Apr 1
40 15008459 Oridonin induced A375-S2 cell apoptosis via bax-regulated caspase pathway activation, dependent on the cytochrome c/caspase-9 apoptosome. 2004 Jun 2
41 15132839 Oridonin induces apoptosis of HeLa cells via altering expression of Bcl-2/Bax and activating caspase-3/ICAD pathway. 2004 May 3