Etoposide

BCL2 associated X, apoptosis regulator ; Homo sapiens







60 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34674796 Pulsed electromagnetic field potentiates etoposide-induced MCF-7 cell death. 2022 Mar 1
2 34411980 Structural optimization, synthesis and in vitro synergistic anticancer activities of combinations of new N3-substituted dihydropyrimidine calcium channel blockers with cisplatin and etoposide. 2021 Oct 1
3 31551763 A Novel Drug Resistance Mechanism: Genetic Loss of Xeroderma Pigmentosum Complementation Group C (XPC) Enhances Glycolysis-Mediated Drug Resistance in DLD-1 Colon Cancer Cells. 2019 1
4 30213983 Etoposide-resistance in a neuroblastoma model cell line is associated with 13q14.3 mono-allelic deletion and miRNA-15a/16-1 down-regulation. 2018 Sep 13 1
5 27419628 Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells. 2016 Aug 23 1
6 25109285 Sirt1 induction confers resistance to etoposide-induced genotoxic apoptosis in thyroid cancers. 2014 Nov 1
7 23161404 Pharmacological inhibition of GSK3 attenuates DNA damage-induced apoptosis via reduction of p53 mitochondrial translocation and Bax oligomerization in neuroblastoma SH-SY5Y cells. 2013 Mar 1
8 23782464 BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove. 2013 Jun 19 1
9 22238053 Quantitative expression analysis of the apoptosis-related genes BCL2, BAX and BCL2L12 in gastric adenocarcinoma cells following treatment with the anticancer drugs cisplatin, etoposide and taxol. 2012 Jun 2
10 22529100 The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1. 2012 Apr 30 1
11 23089312 TIS21(/BTG2/PC3) accelerates the repair of DNA double strand breaks by enhancing Mre11 methylation and blocking damage signal transfer to the Chk2(T68)-p53(S20) pathway. 2012 Dec 1 1
12 20865015 INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis. 2011 Mar 1
13 22072718 Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis. 2011 Dec 30 1
14 20174550 Anaplasma phagocytophilum Ats-1 is imported into host cell mitochondria and interferes with apoptosis induction. 2010 Feb 19 1
15 20226587 Potentiation of etoposide-induced apoptosis in HeLa cells by co-treatment with KG-135, a quality-controlled standardized ginsenoside formulation. 2010 Aug 1 3
16 20840860 p53 and PPP1R13L (alias iASPP or RAI) form a feedback loop to regulate genotoxic stress responses. 2010 Dec 1
17 19657228 The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor. 2009 Sep 1
18 18071312 Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. 2008 May 15 1
19 18330707 Mitochondrial localization and pro-apoptotic effects of the interferon-inducible protein ISG12a. 2008 Apr 1
20 18366759 Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity. 2008 Mar 26 1
21 19271688 Quantitative analysis of expression level of BCL2 and BAX genes in Hep-2 and HL-60 cells after treatment with etoposide. 2008 2
22 17252195 Cyclin-dependent protein kinase 2 activity is required for mitochondrial translocation of Bax and disruption of mitochondrial transmembrane potential during etoposide-induced apoptosis. 2007 Jul 2
23 16211087 Transfection of Smac sensitizes tumor cells to etoposide-induced apoptosis and eradicates established human hepatoma in vivo. 2006 Apr 1
24 16297990 Adrenomedullin prevents apoptosis in prostate cancer cells. 2006 Jan 15 1
25 16325212 The p33ING1b tumor suppressor cooperates with p53 to induce apoptosis in response to etoposide in human osteosarcoma cells. 2006 Feb 23 1
26 16547931 The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax. 2006 Jul 1
27 16709574 JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. 2006 Jul 28 2
28 16895478 Treatment of MCF-7 cells with taxol and etoposide induces distinct alterations in the expression of apoptosis-related genes BCL2, BCL2L12, BAX, CASPASE-9 and FAS. 2006 Aug 2
29 15388581 Mechanistic role of heat shock protein 70 in Bcr-Abl-mediated resistance to apoptosis in human acute leukemia cells. 2005 Feb 1 1
30 15191662 [p33(ING1b) enhances chemosensitivity of osteosarcoma cell U2OS to etoposide]. 2004 Jun 1
31 12823542 Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703. 2003 Jul 2
32 11864976 The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. 2002 May 10 1
33 12063570 Ciprofloxacin inhibits cell growth and synergises the effect of etoposide in hormone resistant prostate cancer cells. 2002 Jul 1
34 12065845 E2F-1 gene therapy induces apoptosis and increases chemosensitivity in human pancreatic carcinoma cells. 2002 Mar-Apr 1
35 11355877 Trail-induced apoptosis in Type I leukemic cells is not enhanced by overexpression of bax. 2001 May 25 2
36 11401473 Vitamin C augments chemotherapeutic response of cervical carcinoma HeLa cells by stabilizing P53. 2001 Mar 30 1
37 11484935 Anticancer drugs induce necrosis of human endothelial cells involving both oncosis and apoptosis. 2001 Jun 1
38 11487718 Subcellular redistribution of BAX during apoptosis induced by anticancer drugs. 2001 Aug 3
39 11513857 The protonophore CCCP induces mitochondrial permeability transition without cytochrome c release in human osteosarcoma cells. 2001 Aug 10 1
40 11521193 Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis. 2001 Aug 9 8
41 11848465 Restoration of bax in prostate cancer suppresses tumor growth and augments therapeutic cell death induction. 2001 Sep-Oct 1
42 11911275 Potential of the proteasomal inhibitor MG-132 as an anticancer agent, alone and in combination. 2001 Nov-Dec 1
43 10620629 Epigenetic determinants of resistance to etoposide regulation of Bcl-X(L) and Bax by tumor microenvironmental factors. 2000 Jan 5 4
44 10713725 Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. 2000 Jan 1
45 10769693 Enhancement of chemotherapeutic agents induced-apoptosis associated with activation of c-Jun N-terminal kinase 1 and caspase 3 (CPP32) in bax-transfected gastric cancer cells. 2000 Jan-Feb 1
46 10839193 Differential responses of Bcl-2 family genes to etoposide in chronic myeloid leukemia K562 cells. 2000 Mar 2
47 10918609 Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells. 2000 Jul 20 1
48 10996201 Altered expression of DNA-topoisomerase IIalpha is associated with increased rate of spontaneous polyploidization in etoposide resistant K562 cells. 2000 Oct 1
49 11029754 N-terminal cleavage of bax by calpain generates a potent proapoptotic 18-kDa fragment that promotes bcl-2-independent cytochrome C release and apoptotic cell death. 2000 Sep 18 1
50 11042671 Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells. 2000 Sep 4