nutlin 3

tumor protein p73 ; Homo sapiens







5 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 20812030 Mdm2 inhibition induces apoptosis in p53 deficient human colon cancer cells by activating p73- and E2F1-mediated expression of PUMA and Siva-1. 2011 Jan 1
2 20305378 Inactivation of p53 signaling by p73 or PTEN ablation results in a transformed phenotype that remains susceptible to Nutlin-3 mediated apoptosis. 2010 Apr 1 1
3 20422343 Disruption of p73-MDM2 binding synergizes with gemcitabine to induce apoptosis in HuCCT1 cholangiocarcinoma cell line with p53 mutation. 2010 Aug 2
4 17700533 HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function. 2008 Feb 7 4
5 18521084 E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines. 2008 Sep 11 1