Tretinoin

aldehyde dehydrogenase family 1, subfamily A1 ; Mus musculus







63 Article(s)
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1 34687254 A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes. 2022 Mar 1
2 35159132 Towards a Better Vision of Retinoic Acid Signaling during Eye Development. 2022 Jan 19 1
3 35493071 Retinol Binding Protein 7 Promotes Adipogenesis in vitro and Regulates Expression of Genes Involved in Retinol Metabolism. 2022 1
4 34085926 Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid. 2021 Jun 4 1
5 34623260 Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction. 2021 Oct 8 2
6 31959382 Regulation of skin fibrosis by RALDH1-producing dermal dendritic cells via retinoic acid-mediated regulatory T cell induction: A role in scleroderma. 2020 Feb 3
7 32295802 Regulation of Gene Expression through Gut Microbiota-Dependent DNA Methylation in Colonic Epithelial Cells. 2020 Apr 15 1
8 32385093 Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. 2020 May 20 1
9 30250298 Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas. 2019 Feb 1
10 30338372 Leishmania donovani reduces the levels of retinoic acid-synthesizing enzymes in infected macrophages and favoring its own survival. 2019 Jan 1
11 30837649 ALDH1A1 regulates postsynaptic μ-opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling. 2019 Mar 5 4
12 31235250 The isoflavone puerarin induces Foxp3+ regulatory T cells by augmenting retinoic acid production, thereby inducing mucosal immune tolerance in a murine food allergy model. 2019 Aug 27 1
13 28919001 Pharmacological inhibition of ALDH1A enzymes suppresses weight gain in a mouse model of diet-induced obesity. 2018 Jan - Feb 1
14 29144959 Induction of innervation by encapsulated adipocytes with engineered vitamin A metabolism. 2018 Feb 2
15 27840061 Endogenous retinoic acid signaling is required for maintenance and regeneration of cornea. 2017 Jan 5
16 28666018 Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice. 2017 1
17 28679528 Moderate alcohol intake induces thermogenic brown/beige adipocyte formation via elevating retinoic acid signaling. 2017 Oct 2
18 29095919 Raldh1 promotes adiposity during adolescence independently of retinal signaling. 2017 6
19 26892828 ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries. 2016 Feb 19 3
20 27422020 Col1a1+ perivascular cells in the brain are a source of retinoic acid following stroke. 2016 Jul 15 2
21 24430728 Trichostatin A specifically stimulates gonadotropin FSHβ gene expression in gonadotroph LβT2 cells. 2014 2
22 22933113 Autocrine function of aldehyde dehydrogenase 1 as a determinant of diet- and sex-specific differences in visceral adiposity. 2013 Jan 3
23 23193184 Fenretinide treatment prevents diet-induced obesity in association with major alterations in retinoid homeostatic gene expression in adipose, liver, and hypothalamus. 2013 Mar 1
24 23806210 Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function. 2013 Sep 1 1
25 23951127 Deficiency of retinaldehyde dehydrogenase 1 induces BMP2 and increases bone mass in vivo. 2013 1
26 22222225 Epithelial expression of the cytosolic retinoid chaperone cellular retinol binding protein II is essential for in vivo imprinting of local gut dendritic cells by lumenal retinoids. 2012 Mar 1
27 22555438 Retinaldehyde dehydrogenase 1 coordinates hepatic gluconeogenesis and lipid metabolism. 2012 Jul 1
28 23053054 Retinoic acid synthesis and metabolism are concurrent in the mouse uterus during peri-implantation. 2012 Dec 1
29 21436255 Concerted action of aldehyde dehydrogenases influences depot-specific fat formation. 2011 May 8
30 20054864 Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. 2010 Mar 31 1
31 20134361 Retinoic acid enhances osteogenesis in cranial suture-derived mesenchymal cells: potential mechanisms of retinoid-induced craniosynostosis. 2010 May 1
32 18831967 Keeping an eye on retinoic acid signaling during eye development. 2009 Mar 16 2
33 18992716 Retinoic acid modulates retinaldehyde dehydrogenase 1 gene expression through the induction of GADD153-C/EBPbeta interaction. 2009 Jan 15 2
34 19618468 Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: implications for retinoid balance in gonad development. 2009 Aug 1
35 18082256 Overexpression of stem cell associated ALDH1A1, a target of the leukemogenic transcription factor TLX1/HOX11, inhibits lymphopoiesis and promotes myelopoiesis in murine hematopoietic progenitors. 2008 Jun 1
36 18665267 Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into beta-cells. 2008 Jul 30 1
37 17363914 Immunolocalization of enzymes, binding proteins, and receptors sufficient for retinoic acid synthesis and signaling during the hair cycle. 2007 Jul 2
38 17592014 Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency. 2007 Jul 2
39 16611695 Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. 2006 May 2
40 16207763 Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells. 2005 Nov 2
41 15245423 Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes Aldh1a2 and Aldh1a3 indicate complex regulation. 2004 Aug 2
42 15366004 Raldh2 expression in optic vesicle generates a retinoic acid signal needed for invagination of retina during optic cup formation. 2004 Oct 5
43 12808103 Targeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retina. 2003 Jul 6
44 12834868 Retinoic acid signaling regulates murine bronchial tubule formation. 2003 Jun 1
45 12851412 Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid. 2003 Sep 19 3
46 11744377 Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. 2002 Jan 1
47 11872149 4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cells exposed to all-trans retinal. 2002 2
48 11959834 Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice. 2002 May 3
49 12454286 Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo. 2002 Dec 10 1
50 11306068 Genetic dissection of retinoid dehydrogenases. 2001 Jan 30 3