Irinotecan

erb-b2 receptor tyrosine kinase 2 ; Homo sapiens







21 Article(s)
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Pub. Year
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1 34268956 Efficacy of trastuzumab combined with SOX or IP chemotherapy regimen in the treatment of advanced gastric cancer. 2021 May-Jun 2
2 32503654 Does a ketogenic diet as an adjuvant therapy for drug treatment enhance chemotherapy sensitivity and reduce target lesions in patients with locally recurrent or metastatic Her-2-negative breast cancer? Study protocol for a randomized controlled trial. 2020 Jun 5 1
3 31466383 Quantifying Risk Pathway Crosstalk Mediated by miRNA to Screen Precision drugs for Breast Cancer Patients. 2019 Aug 28 1
4 28526406 Trastuzumab emtansine suppresses the growth of HER2-positive small-cell lung cancer in preclinical models. 2017 Jul 8 1
5 28850174 Chemotherapy for advanced gastric cancer. 2017 Aug 29 1
6 25601188 Favorable response to trastuzumab plus irinotecan combination therapy in two patients with HER2-positive relapsed small-cell lung cancer. 2015 Mar 3
7 25885574 A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol. 2015 Feb 21 1
8 25890497 The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2. 2015 May 10 2
9 26439663 Synthesis, characterization and targeting chemotherapy for ovarian cancer of trastuzumab-SN-38 conjugates. 2015 Dec 28 3
10 26634139 CPT-11/bevacizumab for the treatment of refractory brain metastases in patients with HER2-neu-positive breast cancer. 2015 Apr 2
11 22124996 Phase II study of bi-weekly irinotecan for patients with previously treated HER2-negative metastatic breast cancer: KMBOG0610B. 2013 Apr 1
12 22973964 Irinotecan resistance is accompanied by upregulation of EGFR and Src signaling in human cancer models. 2013 1
13 23852648 A phase II trial of trastuzumab combined with irinotecan in patients with advanced HER2-positive chemo-refractory gastric cancer: Osaka Gastrointestinal Cancer Chemotherapy Study Group OGSG1203 (HERBIS-5). 2013 Aug 1
14 22213294 Trastuzumab has opposing effects on SN-38-induced double-strand breaks and cytotoxicity in HER2-positive gastric cancer cells depending on administration sequence. 2012 Jan 1
15 22389470 HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer. 2012 Apr 3
16 23335549 Electrolyte abnormalities due to irinotecan administration in metastatic HER-2 positive breast cancer patients. 2012 Oct-Dec 1
17 21868346 [Efficacy of trsatuzumab (Herceptin) combined with FOLFIRI regimen in the treatment of HER2-positive advanced gastric cancer]. 2011 Aug 1
18 21985855 Successful treatment of a patient with HER2-positive metastatic gastric cancer with third-line combination therapy with irinotecan, 5-fluorouracil, leucovorin and trastuzumab (FOLFIRI-T). 2011 1
19 20238327 Chemotherapy for advanced gastric cancer. 2010 Mar 17 1
20 19461176 [Evaluation of irinotecan hydrochloride (CPT-11) and trastuzumab combination therapy as salvage treatment in patients with HER2 overexpressing metastatic breast cancer]. 2009 May 3
21 15641483 Low overexpression of HER-2/neu in advanced colorectal cancer limits the usefulness of trastuzumab (Herceptin) and irinotecan as therapy. A phase II trial. 2004 2