Fluorouracil

caspase 8 ; Homo sapiens







32 Article(s)
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1 32247004 Protective effect of Andrographolide on 5-Fu induced intestinal mucositis by regulating p38 MAPK signaling pathway. 2020 Jul 1 1
2 29695684 Effects of Recombinant Circularly Permuted Tumor Necrosis Factor (TNF)-Related Apoptosis-Inducing Ligand (TRAIL) (Recombinant Mutant Human TRAIL) in Combination with 5-Fluorouracil in Human Colorectal Cancer Cell Lines HCT116 and SW480. 2018 Apr 26 1
3 29921390 Anti-tumor mechanism of IL-21 used alone and in combination with 5-fluorouracil in vitro on human gastric cancer cells. 2018 May-Jun 1
4 26785286 5-Fluorouracil-Induced Apoptosis Changes in Cultured Corneal Epithelial Cells. 2016 Apr 1
5 27462786 Polo-like kinase 3 and phosphoT273 caspase-8 are associated with improved local tumor control and survival in patients with anal carcinoma treated with concomitant chemoradiotherapy. 2016 Aug 16 1
6 25906152 Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. 2015 Apr 23 1
7 26692822 Arsenic trioxide reduces chemo-resistance to 5-fluorouracil and cisplatin in HBx-HepG2 cells via complex mechanisms. 2015 1
8 23108402 5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells. 2013 Sep 19 1
9 23451189 Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-κB and Src protein kinase signaling pathways. 2013 1
10 20876774 Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells. 2011 Feb 2
11 20132554 Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation. 2010 Feb 4 2
12 19097688 Andrographolide enhances 5-fluorouracil-induced apoptosis via caspase-8-dependent mitochondrial pathway involving p53 participation in hepatocellular carcinoma (SMMC-7721) cells. 2009 Apr 18 3
13 19928967 The molecular effects of aloe-emodin (AE)/liposome-AE on human nonmelanoma skin cancer cells and skin permeation. 2009 Dec 2
14 17637740 Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells. 2008 Jan 31 2
15 18082672 The immunocytokine scFv23/TNF targeting HER-2/neu induces synergistic cytotoxic effects with 5-fluorouracil in TNF-resistant pancreatic cancer cell lines. 2008 Feb 15 1
16 19189638 Role of caspases in 5-FU and selenium-induced growth inhibition of colorectal cancer cells. 2008 Nov-Dec 3
17 17016659 Combination of 5-FU and IFNalpha enhances IFN signaling pathway and caspase-8 activity, resulting in marked apoptosis in hepatoma cell lines. 2006 Nov 4
18 17054996 Mitogen-activated protein kinases and chemoresistance in pancreatic cancer cells. 2006 Dec 1
19 15608676 A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation. 2005 Feb 17 1
20 16491956 Irinotecan/5-fluorouracil combination induces alterations in mitochondrial membrane potential and caspases on colon cancer cell lines. 2005 3
21 15105837 Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. 2004 Jul 2
22 15130763 Involvement of tyrosine kinase p56/Lck in apoptosis induction by anticancer drugs. 2004 May 15 1
23 15585135 Proteomic analysis of antiproliferative effects by treatment of 5-fluorouracil in cervical cancer cells. 2004 Nov 1
24 12692863 5-Fluorouracil efficiently enhanced apoptosis induced by adenovirus-mediated transfer of caspase-8 in DLD-1 colon cancer cells. 2003 Apr 2
25 12773255 [Role of caspase-8 and caspase-3 in hepatoma cells apoptosis induced by 5-fluorouracil]. 2003 May 1
26 14607657 Caspase-8 in apoptosis of hepatoma cell induced by 5-fluorouracil. 2003 Feb 11
27 12414664 Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells. 2002 Nov 1 1
28 11264006 5-Fluorouracil suppression of NF-KappaB is mediated by the inhibition of IKappab kinase activity in human salivary gland cancer cells. 2001 Mar 23 1
29 10779637 Morphological change, loss of deltapsi(m) and activation of caspases upon apoptosis of colorectal adenocarcinoma induced by 5-FU. 2000 May 29 1
30 10891390 5-Fluorouracil induces apoptosis through the suppression of NF-kappaB activity in human salivary gland cancer cells. 2000 Jul 14 2
31 11062731 Involvement of caspases in 5-FU induced apoptosis in an oral cancer cell line. 2000 Sep-Oct 1
32 10568827 Apoptosis of colorectal adenocarcinoma induced by 5-FU and/or IFN-gamma through caspase 3 and caspase 8. 1999 Dec 4