Protein Name | fibronectin 1 |
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Organism | Rattus norvegicus |
Gene ID | 25661 |
Gene Symbol | Fn1 |
UniProt | F1LST1 (F1LST1_RAT), A0A096P6L8 (A0A096P6L8_RAT) |
Relationships |
Total Number of functionally related compound(s) :
654
Total Number of Articles : 1012 |
Description |
fibronectin 1 |
Gene Summary |
Enables mercury ion binding activity and protease binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to mercury ion; and cellular response to peptide. Located in basement membrane and extracellular space. Used to study diabetic angiopathy; hypertension; and renovascular hypertension. Biomarker of several diseases, including artery disease (multiple); calcium oxalate nephrolithiasis; iron deficiency anemia; membranoproliferative glomerulonephritis; and ureteral obstruction. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis; membranoproliferative glomerulonephritis; and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |