Protein Name fibronectin 1
Organism Rattus norvegicus
Gene ID 25661
Gene Symbol

Fn1

UniProt F1LST1 (F1LST1_RAT), A0A096P6L8 (A0A096P6L8_RAT)
Relationships Total Number of functionally related compound(s) : 654
Total Number of Articles : 1012
Description

fibronectin 1

Gene Summary

Enables mercury ion binding activity and protease binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to mercury ion; and cellular response to peptide. Located in basement membrane and extracellular space. Used to study diabetic angiopathy; hypertension; and renovascular hypertension. Biomarker of several diseases, including artery disease (multiple); calcium oxalate nephrolithiasis; iron deficiency anemia; membranoproliferative glomerulonephritis; and ureteral obstruction. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis; membranoproliferative glomerulonephritis; and spondylometaphyseal dysplasia corner fracture type. Orthologous to human FN1 (fibronectin 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • fibronectin
  • FN
  • fibronectin 2
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Properties