Protein Name solute carrier family 2 (facilitated glucose transporter), member 4
Organism Mus musculus
Gene ID 20528
Gene Symbol

Slc2a4

UniProt P14142 (GLUT4_MOUSE)
Relationships Total Number of functionally related compound(s) : 479
Total Number of Articles : 815
Description

solute carrier family 2 (facilitated glucose transporter), member 4

Gene Summary

Enables glucose transmembrane transporter activity. Involved in cellular response to insulin stimulus. Acts upstream of or within several processes, including amylopectin biosynthetic process; brown fat cell differentiation; and glucose import in response to insulin stimulus. Located in several cellular components, including cytoplasmic vesicle; extracellular exosome; and sarcolemma. Is integral component of plasma membrane. Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; brain; and genitourinary system. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC2A4 (solute carrier family 2 member 4). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • solute carrier family 2, facilitated glucose transporter member 4
  • glucose transporter type 4, insulin-responsive
  • GT2
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Properties