Protein Name retinoic acid receptor, beta
Organism Mus musculus
Gene ID 218772
Gene Symbol

Rarb

UniProt P22605 (RARB_MOUSE), Q6DFX0 (Q6DFX0_MOUSE)
Relationships Total Number of functionally related compound(s) : 95
Total Number of Articles : 152
Description

retinoic acid receptor, beta

Gene Summary

Enables DNA-binding transcription factor activity and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including animal organ development; regulation of apoptotic process; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in asbestos-related lung carcinoma; lung adenocarcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and syndromic microphthalmia 12. Orthologous to human RARB (retinoic acid receptor beta). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • retinoic acid receptor beta
  • RAR-beta
  • nuclear receptor subfamily 1 group B member 2
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Properties