| Protein Name | retinoic acid receptor, alpha |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19401 |
| Gene Symbol | Rara |
| UniProt | P11416 (RARA_MOUSE), Q3U3R3 (Q3U3R3_MOUSE), Q3U5E7 (Q3U5E7_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
163
Total Number of Articles : 378 |
Description |
retinoic acid receptor, alpha |
| Gene Summary |
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in several processes, including Sertoli cell fate commitment; cellular response to lipopolysaccharide; and germ cell development. Acts upstream of or within several processes, including animal organ development; negative regulation of cartilage development; and regulation of cellular macromolecule biosynthetic process. Located in several cellular components, including dendrite; neuronal cell body; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human RARA (retinoic acid receptor alpha). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |