Protein Name alanine--glyoxylate aminotransferase
Organism Homo sapiens
Gene ID 189
Gene Symbol

AGXT

UniProt P21549 (SPYA_HUMAN)
Relationships Total Number of functionally related compound(s) : 302
Total Number of Articles : 388
Description

alanine--glyoxylate aminotransferase

Gene Summary

This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. [provided by RefSeq, Jul 2008]

synonyms
  • alanine--glyoxylate aminotransferase
  • L-alanine: glyoxylate aminotransferase 1
  • alanine--glyoxylate and serine--pyruvate aminotransferase
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Properties