Protein Name | DNA methyltransferase 3 alpha |
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Organism | Homo sapiens |
Gene ID | 1788 |
Gene Symbol | DNMT3A |
UniProt | Q9Y6K1 (DNM3A_HUMAN), Q59HC6 (Q59HC6_HUMAN), F8WE91 (F8WE91_HUMAN), A0A0C4DG02 (A0A0C4DG02_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
242
Total Number of Articles : 327 |
Description |
DNA methyltransferase 3 alpha |
Gene Summary |
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016] |
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