Protein Name DNA methyltransferase 3 alpha
Organism Homo sapiens
Gene ID 1788
Gene Symbol

DNMT3A

UniProt Q9Y6K1 (DNM3A_HUMAN), Q59HC6 (Q59HC6_HUMAN), F8WE91 (F8WE91_HUMAN), A0A0C4DG02 (A0A0C4DG02_HUMAN)
Relationships Total Number of functionally related compound(s) : 242
Total Number of Articles : 327
Description

DNA methyltransferase 3 alpha

Gene Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]

synonyms
  • DNA (cytosine-5)-methyltransferase 3A
  • DNA (cytosine-5-)-methyltransferase 3 alpha
  • DNA MTase HsaIIIA
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Properties