Title : Amyloidogenesis of SARS-CoV-2 Spike Protein.

Pub. Date : 2022 May 25

PMID : 35579205






1 Functional Relationships(s)
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1 All seven peptides in isolation formed aggregates during incubation at 37 C. Three 20-amino acid long synthetic spike peptides (sequence 192-211, 601-620, 1166-1185) fulfilled three amyloid fibril criteria: nucleation dependent polymerization kinetics by ThT, Congo red positivity, and ultrastructural fibrillar morphology. Peptides surface glycoprotein Severe acute respiratory syndrome coronavirus 2