Title : p53 in ferroptosis regulation: the new weapon for the old guardian.

Pub. Date : 2022 May

PMID : 35087226






1 Functional Relationships(s)
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1 Unlike apoptotic cell death, activation of p53 alone is not sufficient to induce ferroptosis directly; instead, through its metabolic targets, p53 is able to modulate the ferroptosis response in the presence of ferroptosis inducers such as GPX4 inhibitors or high levels of ROS. ros tumor protein p53 Homo sapiens