Title : Hirsutanol A inhibits T-acute lymphocytic leukemia Jurkat cell viability through cell cycle arrest and p53-dependent induction of apoptosis.

Pub. Date : 2021 Jul

PMID : 34055057






1 Functional Relationships(s)
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1 Of note, hirsutanol A induced the expression of the tumor suppressor p53, whereas simultaneous treatment with pifithrin-alpha, an inhibitor of p53, significantly reduced Jurkat cell apoptosis induced by hirsutanol A. pifithrin tumor protein p53 Homo sapiens