Title : Decreased p53 is associated with a decline in asymmetric stem cell self-renewal in aged human epidermis.

Pub. Date : 2021 Feb

PMID : 33524216






1 Functional Relationships(s)
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1 Nutlin-3 increased Notch signaling (NICD, Hes1) and DAPT inhibition of Notch activation prevented Nutlin-3 (p53)-induced asymmetric SC self-renewal divisions in aged keratinocytes. nutlin 3 tumor protein p53 Homo sapiens