Title : MDM2 Inhibition in a Subset of Sarcoma Cell Lines Increases Susceptibility to Radiation Therapy by Inducing Senescence in the Polyploid Cells.

Pub. Date : 2020 Mar-Apr

PMID : 32280825






1 Functional Relationships(s)
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1 Presence and activation of p53 are required for exertion of the radiosensitizing effect by nutlin-3, but this is not the sole determinant of the effect. nutlin 3 tumor protein p53 Homo sapiens