Title : ROS/p53/miR‑335‑5p/Sp1 axis modulates the migration and epithelial to mesenchymal transition of JEG‑3 cells.

Pub. Date : 2020 Mar

PMID : 31894323






1 Functional Relationships(s)
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1 The present results suggested that miR-335-5p expression levels in trophoblast cells could be increased by ROS in a p53-dependent manner, leading to the downregulation of Sp1 and subsequent inhibition of epithelial to mesenchymal transition and cell migration. Reactive Oxygen Species tumor protein p53 Homo sapiens